Protein Alignment CycH and cic-1

DIOPT Version :9

• Sequence 1: NP_524207.1
• Gene: CycH / 40429
• FlyBaseID: FBgn0022936
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_497548.2
• Gene: cic-1 / 175357
• WormBaseID: WBGene00000506
• Length: 302
• Species: Caenorhabditis elegans
• Alignment Length: 310
• Identity: 77/310 - (24%)
• Similarity: 141/310 - (45%)
• Gaps: 53/310 - (17%)

  Fly     5 SSQKRSWTFANEGQLMEFRVEQNSKYIESHEEEAQGRDLN---EHFLTSAEERLLLKQYEIYLFD 66
            ||..:.|.| ::.::.:.|.|.    ::.:.||...| ||   .:|:|:........|..:
 Worm     8 SSHCQQWIF-DKTEIWKQRAED----MKIYNEEEYNR-LNIFWANFITAVATEGAHSQANV---- 62

  Fly    67 FCRRFEPTMPKCVVGTAFHYFKRFYLNNSPMDYHPKEILATCVFVACKVEEF-NVSINQFVNNIK 130
            .|:     :.:.|:.||..|||||||..|..|..|..:.:|.:|:||||||. .:|::.|:.|..
 Worm    63 GCK-----LRQQVIATAIIYFKRFYLRQSFRDMCPFLVASTALFLACKVEEHTTLSVSSFLKNTA 122

  Fly   131 -------GDRNKATD----IVLSNELLLIGQLNYYLTIHNPFRPIEGFLIDIK------TRSN-- 176
                   |...:.|.    :|..:|.:|:..|:..|.:|:..||:...|.|:|      |.:|
 Worm   123 IVLPKRWGVTFETTSTKNGVVYDSEFILVEILDCCLVVHHASRPMFELLEDLKQFTQQSTIANQP 187

  Fly   177 MQNPDRLRPHIDSFIDSTYYSDACLLHTPSQIALAAVLHAAS--REQENLDSYV----TDLLFVS 235
            :::.:.:........:.:...|..|:..|..|.|::::.|..  ...|.|::::    ||.
 Worm   188 IKDLEAIEAQCQKVANDSLRCDVSLIFPPHVIGLSSIMVAMELMGRGEELEAWLVEVDTDF---- 248

  Fly   236 AREKLPGLIDAVRKIRIMVKQYQQPDREKVKAIEKKLDKCRNQANNPDSE 285
              ||:...::.:.|:..:.|.:.  ::|:||.:..||.| .||...|..:
 Worm   249 --EKVTDCVEQIYKMYTLWKSFD--EKEEVKKLMAKLPK-PNQQPPPQQQ 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycH	NP_524207.1	ccl1	2..307	CDD:129660	77/310 (25%)
		CYCLIN	63..>127	CDD:238003	24/64 (38%)
		Cyclin_C_2	159..257	CDD:293504	21/111 (19%)
cic-1	NP_497548.2	CYCLIN	64..>108	CDD:238003	20/48 (42%)
		CYCLIN	162..261	CDD:294043	19/104 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8057
eggNOG	1	0.900	-	-		E1_COG5333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810