Protein Alignment YY2 and Yy2

DIOPT Version :10

• Sequence 1: NP_996806.2
• Gene: YY2 / 404281
• HGNCID: 31684
• Length: 372
• Species: Homo sapiens
• Sequence 2: NP_001364162.1
• Gene: Yy2 / 103690827
• RGDID: 2324567
• Length: 376
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 214/371 - (57%)
• Similarity: 270/371 - (72%)
• Gaps: 17/371 - (4%)

Human    10 TQDLEIPADIVELHDIN-VEPLPMEDIPTESVQ-YEDVDGNWIYGGHNHPPLMVLQPLF-TNTGY 71
            |::.|||||.|||..:: :|.:.:|...::::: |.||..:|.:|||.|.||:.||||. :|...
  Rat    13 TENAEIPADFVELQPLDEIETVSLETNVSQTIEVYGDVGVDWAHGGHYHSPLIALQPLAGSNLSN 77

Human    72 GDHDQEMLMLQTQEEVVGYCDSDN-QLGNDLEDQLALPDSIEDEHFQMTLASLSASAASTSTSTQ 135
            |||||||:::||:||||.|.|||| .||.:.|.|:.||.: ||::.|.|.|:.|...|
  Rat    78 GDHDQEMIIVQTREEVVDYQDSDNLLLGTEFESQMVLPVN-EDDYLQPTTATFSGFMA------- 134

Human   136 SRSKKPSKKPSGKS----ATSTEAN-PAGSSSSLGTRKWEQKQMQVKTLEGEFSVTMWSPNDNND 195
            :.:.:....|.|.:    .|..||. ..|.:..||.::|||||:|:..|:|||...||..|:..:
  Rat   135 AENGQDELSPYGGNLCGLTTIIEAGAEEGVNPDLGDKQWEQKQIQIDGLDGEFPFAMWEDNNLKE 199

Human   196 QGAVGEGQAENPPDYSEYLKGKKLPPGGLPGIDLSDPKQLAEFTKVKPKRSKGEPPKTVPCSYSG 260
            .....|...|:.||||||:.|||.||.|:|||||||||||||||.:|||:.||:.|:.|.||:.|
  Rat   200 DPVAEEEAGESTPDYSEYMTGKKFPPEGIPGIDLSDPKQLAEFTSMKPKKPKGDFPRPVACSHKG 264

Human   261 CEKMFRDYAAMRKHLHIHGPRVHVCAECGKAFLESSKLRRHQLVHTGEKPFQCTFEGCGKRFSLD 325
            |.|||:|.:|||||||||||||||||||||||:|||||:|||||||||||:||||||||:|||||
  Rat   265 CGKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLD 329

Human   326 FNLRTHLRIHTGDKPFVCPFDVCNRKFAQSTNLKTHILTHVKTKNN 371
            ||||||:||||||||||||||.||:|||||||||:|||||||.||:
  Rat   330 FNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKND 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YY2	NP_996806.2	Mediates transcriptional activation	32..102		36/72 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..172		11/50 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..210		6/23 (26%)
		Mediates transcriptional repression	237..372		110/135 (81%)
		C2H2 Zn finger	256..278	CDD:275368	15/21 (71%)
		COG5048	<283..>357	CDD:227381	66/73 (90%)
		C2H2 Zn finger	285..305	CDD:275368	17/19 (89%)
		C2H2 Zn finger	313..335	CDD:275368	19/21 (90%)
		C2H2 Zn finger	343..365	CDD:275368	18/21 (86%)
Yy2	NP_001364162.1	Mediates transcriptional activation. /evidence=ECO:0000250	36..109		36/72 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..220		8/18 (44%)
		Mediates transcriptional repression. /evidence=ECO:0000250	241..376		110/135 (81%)
		C2H2 Zn finger	263..282	CDD:275368	13/18 (72%)
		COG5048	<287..376	CDD:227381	79/89 (89%)
		C2H2 Zn finger	289..309	CDD:275368	17/19 (89%)
		C2H2 Zn finger	317..339	CDD:275368	19/21 (90%)
		C2H2 Zn finger	347..369	CDD:275368	18/21 (86%)