Protein Alignment eg and Pgr

DIOPT Version :10

• Sequence 1: NP_524206.1
• Gene: eg / 40428
• FlyBaseID: FBgn0000560
• Length: 373
• Species: Drosophila melanogaster
• Sequence 2: NP_074038.2
• Gene: Pgr / 25154
• RGDID: 3317
• Length: 926
• Species: Rattus norvegicus
• Alignment Length: 172
• Identity: 49/172 - (28%)
• Similarity: 73/172 - (42%)
• Gaps: 42/172 - (24%)

  Fly     3 QLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAG-----CKHNGDCVINKKNRTACKACR 62
            ::|.:||:.|:|.|:|..||..||.||.|      |:.|     |....||:::|..|..|.|||
  Rat   558 KICLICGDEASGCHYGVLTCGSCKVFFKR------AMEGQHNYLCAGRNDCIVDKIRRKNCPACR 616

  Fly    63 LRKCLLVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARLQQ 127
            ||||...||...|.:: ::.|..::      .:...|:....|||..:    .|.:|.|  |:..
  Rat   617 LRKCCQAGMVLGGRKF-KKFNKVRV------MRALDGVALPQSVGLPN----ESQTLGQ--RITF 668

  Fly   128 ASNQARQTY------------------QDKTNPCIKSATATT 151
            :.||..|..                  .|.|.|...|:..|:
  Rat   669 SPNQEIQLVPPLINLLMSIEPDVVYAGHDNTKPDTSSSLLTS 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eg	NP_524206.1	NR_DBD_like	3..87	CDD:413390	33/88 (38%)
Pgr	NP_074038.2	Prog_receptor	1..557	CDD:460470
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49
		LXXL motif 1. /evidence=ECO:0000250|UniProtKB:P06401	56..60
		LXXL motif 2. /evidence=ECO:0000250|UniProtKB:P06401	116..120
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..240
		Mediates transcriptional transrepression (in isoform A). /evidence=ECO:0000250|UniProtKB:P06401	166..305
		Nuclear localization signal. /evidence=ECO:0000255	185..189
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..372
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..436
		AF1, mediates transcriptional activation. /evidence=ECO:0000250|UniProtKB:P06401	453..539
		NR_DBD_GR_PR	556..633	CDD:143546	32/81 (40%)
		NR_LBD_PR	679..926	CDD:132759	5/32 (16%)
		AF2, mediates transcriptional activation. /evidence=ECO:0000250|UniProtKB:P06401	680..926		5/31 (16%)