DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eg and nhr-195

DIOPT Version :9

Sequence 1:	NP_524206.1	Gene:	eg / 40428	FlyBaseID:	FBgn0000560	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001256111.1	Gene:	nhr-195 / 186625	WormBaseID:	WBGene00019115	Length:	404	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	49/230 - (21%)
Similarity:	72/230 - (31%)	Gaps:	92/230 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIAGCKHNGD--CVINKKNRTACKACRLRKCL 67
            |:||...|.|.|:|..:|..|.:||.|.:........|: .|.  |..|...|..||:||.:||.
Worm    21 CQVCYLRAHGNHYGVVSCRACAAFFRRVFITHKQHFKCQ-GGQMKCEPNSVGRWDCKSCRTKKCF 84

  Fly    68 LVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQLARLQQASNQA 132
            .:||        |..|   |.|                            |.:.::..:...|..
Worm    85 DIGM--------RPDN---IQC----------------------------SDDTISYSESIPNDP 110

  Fly   133 RQTYQDKTNPCIKSATATTSPRIEGAAVGTGIGGGASPSFLQAAKLHHQRQLKLDSRLSNTPSDS 197
            :.|                                :|||.:.::...:.......|.|
Worm   111 KDT--------------------------------SSPSAISSSSEEYITFFDFTSLL------- 136

  Fly   198 GASSAGDPNEDGVTSVLGGQIATPSSTNATSLPKL 232
                      :.:.::|..||.|| .||.|||.||
Worm   137 ----------ESIENILKTQIDTP-ITNQTSLQKL 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eg	NP_524206.1	NR_DBD_like	3..87	CDD:295381	27/83 (33%)
nhr-195	NP_001256111.1	ZnF_C4	20..91	CDD:197701	26/78 (33%)
nhr-195	NP_001256111.1	Hormone_recep	174..376	CDD:365875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1136195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010