DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eg and nhr-110

DIOPT Version :9

Sequence 1:	NP_524206.1	Gene:	eg / 40428	FlyBaseID:	FBgn0000560	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001041195.1	Gene:	nhr-110 / 178651	WormBaseID:	WBGene00003700	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	165	Identity:	48/165 - (29%)
Similarity:	70/165 - (42%)	Gaps:	46/165 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNIAAIA------------GCKHNGDCVINKKNRTA 57
            |:||..|..|.||||:||..|.:||     .|.:|:            .|::|.:|......|..
Worm    26 CQVCFLPGHGIHFGAYTCRACAAFF-----RIVSISKSKCHFSPRPTHKCRNNSNCKPKIDGRWF 85

  Fly    58 CKACRLRKCLLVGMSKSGSRYGRRSNWFKIHCLLQEQQTTSGLGGGSSVGSGSGGGVSSASLEQL 122
            ||.|||.:||.:|||....:|.|.    |...:|:..:....|...::|.|            ||
Worm    86 CKTCRLTRCLSIGMSPENIQYDRD----KFESILKSSKNNRHLQIPNTVES------------QL 134

  Fly   123 --ARLQQASNQARQTYQDKTNPCI------KSATA 149
              :.|...||:     ::|::.||      |.|.|
Worm   135 CISPLVSFSNR-----REKSSKCIDISQIVKKAVA 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eg	NP_524206.1	NR_DBD_like	3..87	CDD:295381	32/93 (34%)
nhr-110	NP_001041195.1	ZnF_C4	25..102	CDD:197701	30/80 (38%)
nhr-110	NP_001041195.1	Hormone_recep	195..407	CDD:365875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1136195at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010