Protein Alignment Syn1 and SLC9A3R2

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_016879383.1
• Gene: SLC9A3R2 / 9351
• HGNCID: 11076
• Length: 372
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 96/500 - (19%)
• Similarity: 139/500 - (27%)
• Gaps: 192/500 - (38%)

  Fly    23 SPSPS----GLRCGNMETRVRGAWYRVLVTLETDFLAVSLDES----CEAAQPSNDGQSTTLNGT 79
            ||.||    |||.|     |||                  |.|    |........|    |.|.
Human     2 SPPPSGGPWGLRAG-----VRG------------------DSSAGGGCVVGARCLRG----LPGF 39

  Fly    80 LGSNHSGGGGG-----GAG--------GGGTGGGGQNGTLPNSASLQGMNIQDTELDGSASNDNG 131
            .||..||...|     |.|        |.|.|.|     ||.::.|..:..:.:.:.|:....:
Human    40 PGSCSSGASTGPSCVLGPGLLPVPSALGPGAGQG-----LPAASFLPFLGRKPSWVGGARLEPS- 98

  Fly   132 DRDPCLNNNNNAGDGGGM--------DMCDVPDHVANQKRHVRIIKSDNNGLGISIKGGRENRMP 188
                         .|.|:        |.......:..:....|.:......||.....|...|.|
Human    99 -------------QGSGLSHHPAPQSDSAPTSPPIPGEPGPQREVDKWGGSLGRPESSGHPGRTP 150

  Fly   189 ILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSGRVVDLEVKFLREVTPYF 253
                                              ||.......:.|||           ..||..
Human   151 ----------------------------------ATCCHCAAVMARSG-----------SATPPA 170

  Fly   254 RKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYIDPENRCFE 318
            |                    .||.|...|..:.......|.:..:|.||.:.     |:...|.
Human   171 R--------------------APGAPPRSPPQRLDVSGPLRELRPRLCHLRKG-----PQGYGFN 210

  Fly   319 LHSPDGVHSCILRAAD-----------SAEALVWFN-----ALHSAMGTSTQRALAEANRALT-- 365
            |||........:|:.|           :.:.|:..|     .|..|...::.:|..:..|.|.
Human   211 LHSDKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVD 275

  Fly   366 ----------NLIGELKHI-GWLSKRMSGGGSSGSAGGGAASGGSGTSNSVVAGELVSPSGRSSS 419
                      .:....:|: |.|...::.|.|.....||:|.    :|.|.:.|         |.
Human   276 PETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSAC----SSRSDLPG---------SD 327

  Fly   420 ESSDESDKWL-PIFVAVTE--REFRIYESAPWSVEAWSRPLEIYA 461
            :.::||...| |......|  |..|:.:.||..  .|:|..||::
Human   328 KDTEESGLHLSPTAAEAKEKARAMRVNKRAPQM--DWNRKREIFS 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	6/30 (20%)
		PDZ_signaling	163..244	CDD:238492	11/80 (14%)
		PHsplit_syntrophin	<293..351	CDD:269960	15/73 (21%)
SLC9A3R2	XP_016879383.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810