Protein Alignment Syn1 and Pdzph1

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_081277.1
• Gene: Pdzph1 / 69239
• MGIID: 1916489
• Length: 1238
• Species: Mus musculus
• Alignment Length: 561
• Identity: 116/561 - (20%)
• Similarity: 176/561 - (31%)
• Gaps: 179/561 - (31%)

  Fly    16 QPIPQQHSPSPSGLRC---GNMETRVRGAWYRVLVTLETDFLAVSLDESCEAAQPSNDGQSTTLN 77
            |..|.:...:.|.:.|   ||.......:.:.|.:.|.........|::.|...|....|...|.
Mouse   735 QQEPAECQRTTSRVYCEESGNQRYPTEVSCHPVDILLSPQKQKALKDQNLEINNPRKLSQELALR 799

  Fly    78 GTLGSNHSGGGGGGAGGGGTGGGGQNGTLPNSA-------------SLQGMNIQDTELDGSASND 129
                            ||....|.|...:...|             |..|.::.....:||.::|
Mouse   800 ----------------GGRASDGSQEEAIEQWARRRQQFKDGKRCSSAGGSSVISNFTEGSITSD 848

  Fly   130 N------GDRDP-------CLNNNNNA----GDGGGMD-----MCDVPDHVANQKRHVRIIKSDN 172
            :      |.|..       ..|.::.|    ||.|..:     :...|..||.::|.||:.|
Mouse   849 DVHSVDFGFRVDIEEKGFYTENFHSTAWVFRGDDGNPEDSPRCLSKKPRPVAVRERTVRLFK--- 910

  Fly   173 NGLGISIKGGR-ENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSG 236
             |.|....|.| :...||:::::....||::| ||.:||.:|:|||.|:....|.|||...|:..
Mouse   911 -GTGDYPWGFRIQFSKPIVVTEVDTNSAAEEA-GLQIGDVVLSVNGTEVTSVEHAEAVHLAKKGL 973

  Fly   237 RVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTT------------- 288
            .::.:.|            ||.||.          ||..|.........|.|
Mouse   974 DILTMVV------------ASDISR----------CPNTPWPTCRGYLHKRTHSGFVKGWRKRWF 1016

  Fly   289 -------------PRADTRYIPLQLTHLARNLKYIDPENR-----CFELHSPDGVHSCILRAADS 335
                         .:.:.::.||.:..|..  ..:|.:|.     .|......|.....|.|..:
Mouse  1017 VLKHDGFLLYYKHRKDEGKWPPLDMIKLEG--AEVDIDNSLGKPFVFNCMPQSGSRILCLCATSN 1079

  Fly   336 AEALVWFNALHSAMGTSTQRALAE----ANRALTNLIGELKH---IG-----------WLSKR-- 380
            .|...|..|:..|.....|..:.|    .|.:|..|  .:||   :|           |:...
Mouse  1080 QEMKRWLEAMQRAARPVHQNHVWEDVTVHNSSLPPL--AIKHPECLGLLHQLERSTDVWIQHYCI 1142

  Fly   381 MSGGG-------SSGSAGGGAASGGSGTSNSVVAGEL----VSPSGRS------SSESSDESD-- 426
            :..|.       .|..|.||....|...|......|.    :.||...      .:|:..|:.
Mouse  1143 LKDGCLYFYASIRSTQASGGLYLQGYSVSEQTHGFEQPVIELKPSSEEFKTFYFCAENKTENQRW 1207

  Fly   427 ---------KWLPIFVAVTEREFRIYESAPWSVEAWSRPLE 458
                     ||||:..|:  :||            .|||||
Mouse  1208 IAALKTSIKKWLPLDQAI--QEF------------MSRPLE 1234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	6/33 (18%)
		PDZ_signaling	163..244	CDD:238492	27/81 (33%)
		PHsplit_syntrophin	<293..351	CDD:269960	13/62 (21%)
Pdzph1	NP_081277.1	PDZ_signaling	903..981	CDD:238492	28/94 (30%)
		PH-like	986..1093	CDD:302622	17/118 (14%)
		PH	993..1094	CDD:278594	15/102 (15%)
		PH-like	1123..1215	CDD:302622	14/91 (15%)
		PH	1125..1216	CDD:278594	13/90 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900