DRSC/TRiP Functional Genomics Resources

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Protein Alignment Syn1 and dlg5a

DIOPT Version :9

Sequence 1:NP_001262192.1 Gene:Syn1 / 40424 FlyBaseID:FBgn0037130 Length:627 Species:Drosophila melanogaster
Sequence 2:XP_005156738.1 Gene:dlg5a / 569065 ZFINID:ZDB-GENE-030131-3149 Length:1961 Species:Danio rerio


Alignment Length:343 Identity:68/343 - (19%)
Similarity:117/343 - (34%) Gaps:120/343 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 PAAQQPIPQQHS-PSPSGLRCGNMETRVRGAWYRVLVTLE------TDFLAVSLDESCEAAQPSN 69
            |.....|.|||: |||.               ::..::|:      ||:     .||..:::.|:
Zfish  1234 PTVVSQINQQHTHPSPQ---------------HQGQLSLDLSQKRSTDY-----SESSRSSRASH 1278

  Fly    70 DGQSTTLNGTLGSNHS---------------------GGGGGGAGGGGTGGGGQNGTLPNS---- 109
            ...|...:..|||:::                                   |...|:|.:|    
Zfish  1279 GTNSLPSSARLGSSNNLQYRTERIKIPSTPRYPRSIL--------------GSDRGSLSHSECSS 1329

  Fly   110 -----ASLQGMNIQDTELDGSASNDNGDRDPCLNNNNNAGDGGGMDMCDVPDH-------VANQK 162
                 ..|..:|::.:....|.|..:....|.::            :..||..       ...:.
Zfish  1330 PSLITPPLSPLNLETSSFASSQSQGSISTLPRIS------------VSPVPTEERRKDRPYLEEP 1382

  Fly   163 RHVRIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDE 227
            |:|.:.|. ...|||||..|...  .|.:||:..|..|.|| ||..||.:|..||..||:||..:
Zfish  1383 RNVMVHKG-AEPLGISIVSGENG--GIFVSKVTGGSIAHQA-GLEYGDQLLEYNGINLRNATEQQ 1443

  Fly   228 AVRALKRSGRVVDLEVKF---LREVTPYFRKASIISEVGWELQRAFLCPLGPGVPT--------- 280
            |...:.:....:.:..::   :.::..:.|.:|.:..|..:     ..|.|.|..|         
Zfish  1444 ARLIIGQQCDTITIMAQYNPHMYQLGNHSRSSSRLEPVSTQ-----STPQGSGTATPDNHSTIDT 1503

  Fly   281 ---------SPPAPKTTP 289
                     :|.:.:|||
Zfish  1504 LSEQDEGTLTPSSKQTTP 1521

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syn1NP_001262192.1 PH-like 30..>61 CDD:302622 3/36 (8%)
PDZ_signaling 163..244 CDD:238492 28/80 (35%)
PHsplit_syntrophin <293..351 CDD:269960
dlg5aXP_005156738.1 CARD 9..88 CDD:260018
Takusan 128..211 CDD:282652
Taxilin 295..627 CDD:286771
RILP-like 338..460 CDD:304877
SH3BP5 444..648 CDD:283045
PDZ_signaling 696..783 CDD:238492
PDZ_signaling 793..866 CDD:238492
PDZ 1381..1463 CDD:214570 28/85 (33%)
dbPDZ_assoc 1461..1541 CDD:293216 11/66 (17%)
PDZ 1541..1623 CDD:214570
SH3_DLG5 1639..1701 CDD:212794
Guanylate_kin 1780..1949 CDD:279019
NK 1794..1950 CDD:302627
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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