DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and CG34375

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001163693.1	Gene:	CG34375 / 42715	FlyBaseID:	FBgn0085404	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	160	Identity:	31/160 - (19%)
Similarity:	61/160 - (38%)	Gaps:	29/160 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 NNGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALK--- 233
            |..||:::.....:..| .:|.:....:|::. |:.:||.:|.:||.::......|....|:
  Fly    12 NGTLGLNLSRAPWDPYP-WVSGVQAKSSAERG-GVRLGDTLLELNGADVLGLKISELANRLQDHW 74

  Fly   234 RSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPL 298
            :||                   |.:::.:.|. |:|.:.|.......|........:...:....
  Fly    75 QSG-------------------AEVVTLMMWR-QQANIDPNEDPAEASHAVQHGINQQSLQKFAT 119

  Fly   299 QLTHLARNLKYIDPENRCFELHSPDGVHSC 328
            .|.|:::.|:.  |.  |.|:..|.|...|
  Fly   120 CLQHISQLLEC--PV--CLEVIKPPGWQCC 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	16/74 (22%)
		PHsplit_syntrophin	<293..351	CDD:269960	9/36 (25%)
CG34375	NP_001163693.1	PDZ	13..86	CDD:238080	16/93 (17%)
CG34375	NP_001163693.1	RING	129..168	CDD:238093	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900