DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and CG42319

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001137648.1	Gene:	CG42319 / 36473	FlyBaseID:	FBgn0259219	Length:	452	Species:	Drosophila melanogaster

Alignment Length:	198	Identity:	45/198 - (22%)
Similarity:	77/198 - (38%)	Gaps:	34/198 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 DNGDRDPCLNNNNNAGDGGGMDMCDVPDHVANQKRHVRIIKSDNNGLGISIKGGRENRMPILISK 193
            ::..:.|.:..:...||..|....||.......|        |::..|..|.||.|..||:.:.:
  Fly    13 ESKSKAPIIKVSCGIGDTDGYPAFDVDSDAYATK--------DDSRWGFLITGGAEFHMPLTVFQ 69

  Fly   194 IFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSGRVVDLEVKFLREVTPYFR---- 254
            :.....||:| |:.:||.||.:|.|:....|..:|...:..:.:.:...::.:.|..|..:
  Fly    70 VTPNGLADKA-GIRLGDIILEINEEDASQLTLSQAHEKINSTPKKIHFLLRNMEEDDPMGQFEAG 133

  Fly   255 -KASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYID--PENRC 316
             :.||:..                ||...|.|....||.:  |.::|..:.|.|..|.  |:..|
  Fly   134 EEKSIVMR----------------VPKPLPPPSGRIRASS--IEMRLLEMQRKLSAIAEIPKILC 180

  Fly   317 FEL 319
            ..|
  Fly   181 STL 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	20/80 (25%)
		PHsplit_syntrophin	<293..351	CDD:269960	8/29 (28%)
CG42319	NP_001137648.1	PDZ_signaling	45..119	CDD:238492	21/82 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900