DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syn1 and Cytip

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001012086.1	Gene:	Cytip / 311047	RGDID:	1307990	Length:	359	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	40/161 - (24%)
Similarity:	62/161 - (38%)	Gaps:	33/161 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 NGTLPNSA--------SLQG-MNIQDTE-----LDGSASNDNGDRDPCLNNNNNAGDGGGMDMCD 153
            ||.|...|        :|.| :.::|..     .|..|:...|.:...|..:::.|
  Rat    13 NGNLEYCADSAYSSYPTLTGPLTVEDNRRIQMLADTVATLPRGRKQLALARSSSLG--------- 68

  Fly   154 VPDHVANQKRHVRIIKSDNNGLGISIKGGRENRMPI-------LISKIFRGMAADQAKGLYVGDA 211
              |...:|::.|.:.|.||...|..|:..|.....|       :|.|:.....|..| ||.|||.
  Rat    69 --DFSCSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCA-GLQVGDI 130

  Fly   212 ILTVNGEELRDATHDEAVRALKRSGRVVDLE 242
            ...|||......||.:.|..::.||.::.:|
  Rat   131 FANVNGVSTEGFTHKQVVDLIRSSGNLLTIE 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	26/87 (30%)
		PHsplit_syntrophin	<293..351	CDD:269960
Cytip	NP_001012086.1	PDZ_signaling	76..161	CDD:238492	25/85 (29%)
Cytip	NP_001012086.1	Interaction with CYTH1. /evidence=ECO:0000250	166..188
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900