Protein Alignment Syn1 and Slc9a3r1

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_036160.1
• Gene: Slc9a3r1 / 26941
• MGIID: 1349482
• Length: 355
• Species: Mus musculus
• Alignment Length: 358
• Identity: 76/358 - (21%)
• Similarity: 121/358 - (33%)
• Gaps: 95/358 - (26%)

  Fly   173 NGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDEAVRALKRSGR 237
            ||.|..:. |.:.::...|..:..|..|::: ||..||.::.||||.:...||.:.|..::.:..
Mouse    22 NGYGFHLH-GEKGKVGQFIRLVEPGSPAEKS-GLLAGDRLVEVNGENVEKETHQQVVSRIRAALN 84

  Fly   238 VVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPLQLTH 302
            .|.|.|     |.|  .....:.::|..::...|.|........|||...|..|..:. ..:.:|
Mouse    85 AVRLLV-----VDP--ETDERLKKLGVSIREELLRPQEKSEQAEPPAAADTHEAGDQN-EAEKSH 141

  Fly   303 LARNLK------YIDPENRCFELHSPDGVHSCILRAADSAEALVWFNALHSAMGTSTQRALAEAN 361
            | |.|:      ...|....|.|||........:||.|.       ::...|.|...|..:.|.|
Mouse   142 L-RELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDP-------DSPAEASGLRAQDRIVEVN 198

  Fly   362 RALTNLIGELKHIGWLSKRMSGGG----------------------------------------- 385
                .:..|.|..|.:...:.|||
Mouse   199 ----GVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFFKKCKVIPSQEHLDGPLPEPFSNGEI 259

  Fly   386 -------------SSGSAGGGAASGGSGTSNSVVAGELVSP----SGRSSSESSDESDKWLPIFV 433
                         |.......|.|..|.||..:.:.:  ||    |...||.||..||..|.:.:
Mouse   260 QKESSREALVEPASESPRPALARSASSDTSEELNSQD--SPKRQVSTEPSSTSSSSSDPILDLNI 322

  Fly   434 AVTEREFRIYES-----APWSVEAWSRPLEIYA 461
            ::...:.|.::.     ||..  .||:..|:::
Mouse   323 SLAVAKERAHQKRSSKRAPQM--DWSKKNELFS 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	20/70 (29%)
		PHsplit_syntrophin	<293..351	CDD:269960	13/63 (21%)
Slc9a3r1	NP_036160.1	PDZ_signaling	12..91	CDD:238492	21/75 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..146		10/37 (27%)
		PDZ_signaling	147..226	CDD:238492	19/89 (21%)
		EBP50_C	230..355	CDD:286142	22/128 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..355		22/114 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900