DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Syn1 and smz-2

DIOPT Version :9

Sequence 1:NP_001262192.1 Gene:Syn1 / 40424 FlyBaseID:FBgn0037130 Length:627 Species:Drosophila melanogaster
Sequence 2:NP_491965.1 Gene:smz-2 / 172415 WormBaseID:WBGene00020661 Length:274 Species:Caenorhabditis elegans


Alignment Length:70 Identity:23/70 - (32%)
Similarity:39/70 - (55%) Gaps:9/70 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 NG--LGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEEL--RDATHDEAVRALK 233
            ||  ||:.|| ..:||  :|:|::..|..|:  |.|.:||.:..|:|..:  :|...|..|:.::
 Worm   119 NGPKLGLGIK-HFQNR--VLVSRVDPGSLAE--KCLVLGDHLCDVDGIPVSDKDVARDLLVKNIQ 178

  Fly   234 RSGRV 238
            ..|:|
 Worm   179 EKGKV 183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syn1NP_001262192.1 PH-like 30..>61 CDD:302622
PDZ_signaling 163..244 CDD:238492 23/70 (33%)
PHsplit_syntrophin <293..351 CDD:269960
smz-2NP_491965.1 PDZ_signaling 7..77 CDD:238492
PDZ_signaling 114..188 CDD:238492 23/70 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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