Protein Alignment Syn1 and Patj

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_038965114.1
• Gene: Patj / 140581
• RGDID: 1565362
• Length: 1858
• Species: Rattus norvegicus
• Alignment Length: 559
• Identity: 116/559 - (20%)
• Similarity: 183/559 - (32%)
• Gaps: 208/559 - (37%)

  Fly     7 LGRTPPAAQQ--------PIPQQHSPSPSGLRCGNMETRVRGAWYRVLVTLETDFLAVSLDESCE 63
            ||.|.|.:.:        |:|::.|..|..|.....::.|          .|.:..:.|.|.:
  Rat  1354 LGGTEPVSSEEDSSVDAKPLPERESSKPEDLTQAVDDSMV----------AEQEKASESPDSA-- 1406

  Fly    64 AAQPSNDGQSTTLNGT-----------LGSNHSGGGGGGAGGGGTGGGGQNGTLPNSASLQGMNI 117
            |.|....|.|..::.:           ..|.|:...|.|           |...|.|.....:::
  Rat  1407 ARQMKQPGYSAQVSSSSQEIPSAPAPLCQSTHADVTGSG-----------NFQAPLSVDPAPLSV 1460

  Fly   118 QDTELDGSASNDNGDRDPCLNNNNNAGDGGGMDMCDVPDHVANQKRHVRIIKSDNNGLGISIKGG 182
                            ||.              .|.:   |..|:..:.|.|. .:|||:||.||
  Rat  1461 ----------------DPA--------------TCPI---VPGQEMIIEISKG-RSGLGLSIVGG 1491

  Fly   183 RENRMP-----------------------ILISKIFRGMAADQAKGLYVGDAILTVNGEELRDAT 224
            ::..:|                       |:|.:::...||.:...|:.||.||.|||.:||.::
  Rat  1492 KDTPLPGGSLPTKVGVWEKKLQEMMSQDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSS 1556

  Fly   225 HDEAVRALKRSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAPKTTP 289
            |:||:.||:::.:.|.|.:        |..:|....|...|:   ||..|          .|.|.
  Rat  1557 HEEAITALRQTPQKVRLVI--------YRDEAQYRDEENLEV---FLVDL----------QKKTG 1600

  Fly   290 RADTRYIPLQLTHLARNLKYIDPENRCFELHSPDGVH-SCILR--AADSAEALVWFNALHSAMGT 351
            |.      |.|:.:.:              .|..||. |.|::  |||....|:..:.:.|..|.
  Rat  1601 RG------LGLSIVGK--------------RSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGE 1645

  Fly   352 STQRA-------LAEANRALTNL-IGELKHIGWLSKRMSGGGSSGSAGGGAAS------------ 396
            ..::|       :.:..:.|..| ||.|:...|.|.|.:...|.|......:|
  Rat  1646 DVRQASQETVATILKCVQGLVQLEIGRLRAGSWASSRKTSQNSQGDQHSAHSSCRPSFAPVITSL 1710

  Fly   397 -GGSGTSNS---------------VVAGEL-----VSPSGRSSSESSDESDKWLPIFVAVTEREF 440
             ...||..|               .:..||     ||.:|...|...|     :|||:|:.:...
  Rat  1711 QNLVGTKRSSDPPQKCTEEEPRTVEIIRELSDALGVSIAGGKGSPLGD-----IPIFIAMIQANG 1770

  Fly   441 RIYESAPWSVEAWSRPLEIYALATTRLAGAGNNSSLNGQ 479
                               .|..|.:|.......|:|||
  Rat  1771 -------------------VAARTQKLKVGDRIVSINGQ 1790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	4/30 (13%)
		PDZ_signaling	163..244	CDD:238492	31/103 (30%)
		PHsplit_syntrophin	<293..351	CDD:269960	12/60 (20%)
Patj	XP_038965114.1	L27_2	8..65	CDD:312549
		PDZ_signaling	135..218	CDD:238492
		PDZ_signaling	248..325	CDD:238492
		PDZ_signaling	366..450	CDD:238492
		CtpA	<391..>511	CDD:223864
		PDZ_signaling	572..636	CDD:238492
		PDZ	684..773	CDD:214570
		PDZ_signaling	1074..1165	CDD:238492
		PDZ	1244..1329	CDD:214570
		PDZ	1471..1578	CDD:214570	33/115 (29%)
		PDZ_signaling	1590..1670	CDD:238492	22/112 (20%)
		PDZ_signaling	1731..1816	CDD:238492	18/84 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810