Protein Alignment Syn1 and Il16

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: XP_006229550.1
• Gene: Il16 / 116996
• RGDID: 1583872
• Length: 1425
• Species: Rattus norvegicus
• Alignment Length: 411
• Identity: 86/411 - (20%)
• Similarity: 148/411 - (36%)
• Gaps: 93/411 - (22%)

  Fly     2 VESSSLGRTPPAAQQPIPQQHSPSP--------------SGLRCGNMETR----VRGAWYRVLVT 48
            |....:..:||..|:|.|:..||.|              .|.:..:...|    .|...|...:.
  Rat  1012 VGDPDMSESPPPGQRPNPKALSPDPLLRLLTTQTEDTQGPGFKMPSQRARSFPLTRTQSYETKLL 1076

  Fly    49 LETDFLAVSLDESCEAA-------QPSND--GQSTTLNGTLGSNHSG-GGGGGAGGGGTGGGGQN 103
            .|......|:.....:|       .||:.  ||.|.:.....|..|. .....|.|.|.......
  Rat  1077 DEKSSKLYSISSQLSSAVMKSLLCLPSSASCGQITCIPKERVSPKSPCNNSAAAEGFGEAVASDT 1141

  Fly   104 GTLPNSASLQGMNIQDTELDGSASNDNGDRDPCLNNNNNAGDG-----GGMDMCDVPDHV----- 158
            |...|.:.|:..:...||     ..:..||:.|   ::.||..     ...::..:.:.|
  Rat  1142 GFSLNLSELREYSEGLTE-----PGETEDRNHC---SSQAGQSVISLLSAEELKKLIEEVRVLDE 1198

  Fly   159 ANQKR----HVRII-KSDNNGLGISIKGGR--ENRMPILISKIFRGMAADQAKGLYVGDAILTVN 216
            |..|:    ||.:: |.:..|||.|:.||.  ||:: |.:.::|....|.|...:..|:.:|::|
  Rat  1199 ATLKQLDSIHVTVLHKEEGAGLGFSLAGGADLENKV-ITVHRVFPNGLASQEGTIQKGNEVLSIN 1262

  Fly   217 GEELRDATHDEAVRALKRS---------GRVVDLEVKF-LREVTPYFRKASIISEVGWELQRAFL 271
            |:.|:.|||::|:..|:::         .|...:|... |...|.....||:.|.:..|...|.:
  Rat  1263 GKSLKGATHNDALAILRQARDPRQAVIVTRKAIVEAAHDLNSSTDSAASASVASGISVESVEATV 1327

  Fly   272 CPL-----GPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKY---IDPENRCFELHS------- 321
            |.:     ..|:..|....|.:...|.   ||.:..:.:..:.   :.|.:...:|..
  Rat  1328 CTVTLEKTSAGLGFSLEGGKGSLHGDK---PLTINRIFKGTEQGDAVQPGDEILQLAGTAVQGLT 1389

  Fly   322 -----------PDGVHSCILR 331
                       |||..:.::|
  Rat  1390 RFEAWNVIKALPDGPVTVVIR 1410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	5/34 (15%)
		PDZ_signaling	163..244	CDD:238492	27/96 (28%)
		PHsplit_syntrophin	<293..351	CDD:269960	8/60 (13%)
Il16	XP_006229550.1	PDZ_signaling	316..391	CDD:238492
		PDZ_signaling	454..536	CDD:238492
		PDZ_signaling	1207..1284	CDD:238492	25/77 (32%)
		PDZ	1329..1413	CDD:214570	12/85 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900