Protein Alignment Syn1 and Slc9a3r2

DIOPT Version :9

• Sequence 1: NP_001262192.1
• Gene: Syn1 / 40424
• FlyBaseID: FBgn0037130
• Length: 627
• Species: Drosophila melanogaster
• Sequence 2: NP_446263.2
• Gene: Slc9a3r2 / 116501
• RGDID: 620380
• Length: 337
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 78/371 - (21%)
• Similarity: 121/371 - (32%)
• Gaps: 117/371 - (31%)

  Fly   163 RHVRIIKSDNNGLGISIKG--GRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATH 225
            |..|:::.: .|.|..:.|  ||..:   .|.::..|..| :|..|..||.::.|||..:...||
  Rat    10 RLCRLVRGE-QGYGFHLHGEKGRRGQ---FIRRVEPGSPA-EAAALRAGDRLVEVNGVNVEGETH 69

  Fly   226 DEAVRALKR-SGR----VVDLEV--KFLREVTPYFRKASIISEVG----------WELQRAFLCP 273
            .:.|:.:|. .|:    |||.|.  :..|      |:.:...|:.          ||.:..:.|.
  Rat    70 HQVVQRIKAVEGQTQLLVVDKETDEELCR------RQLTCTEEMAHRGLPPAHNPWEPKPDWACS 128

  Fly   274 LGPGVPTSPPAPKTTPRADTRYIPLQLTHLARNLKYIDPENRCFELHSPDGVHSCILRAADSAEA 338
            ...|..|........||.    :..:|.||.|.     |:...|.|||........:|:.|....
  Rat   129 GSLGSDTGQKDVNGPPRE----LRPRLCHLRRG-----PQGYGFNLHSDKSRPGQYIRSVDPGSP 184

  Fly   339 LVWFNALHSAMGTSTQRALAEANRALTNLIGELKHI----------------------------- 374
            .       |..|...|..|.|.|.  .|:.| |:|.
  Rat   185 A-------SLSGLRAQDRLIEVNG--QNVEG-LRHAEVVARIKAQEDEARLLVVDPETDEHFKRL 239

  Fly   375 ----------GWLSKRMSGGGSSGSAGGGAASGGSGTSNSVVAGELVSPSGRSSSESSDESDKW- 428
                      |.|...::.|.|.....||:..    :|.|.:.|         |.:.:::...|
  Rat   240 RVVPTEDHVEGPLPSPVTNGTSLAQLNGGSVC----SSRSDLPG---------SEKDNEDGSAWK 291

  Fly   429 -----------LPIFVAVTE--REFRIYESAPWSVEAWSRPLEIYA 461
                       .|......|  |..|:.:.||..  .|:|..||::
  Rat   292 RDPFQESGLHLSPTAAEAKEKARATRVNKRAPQM--DWNRKREIFS 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	26/89 (29%)
		PHsplit_syntrophin	<293..351	CDD:269960	12/57 (21%)
Slc9a3r2	NP_446263.2	PDZ_signaling	9..88	CDD:238492	22/82 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..146		4/18 (22%)
		PDZ_signaling	149..228	CDD:238492	21/93 (23%)
		EBP50_C	232..337	CDD:401087	21/119 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..337		21/105 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810