DRSC/TRiP Functional Genomics Resources

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Protein Alignment Syn1 and USH1C

DIOPT Version :9

Sequence 1:NP_001262192.1 Gene:Syn1 / 40424 FlyBaseID:FBgn0037130 Length:627 Species:Drosophila melanogaster
Sequence 2:XP_016872564.1 Gene:USH1C / 10083 HGNCID:12597 Length:956 Species:Homo sapiens


Alignment Length:123 Identity:38/123 - (30%)
Similarity:64/123 - (52%) Gaps:6/123 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   163 RHVRIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAILTVNGEELRDATHDE 227
            :.||:.:....|||:|::||.|....:.||.:.:|..||.. ||.|||.|:.:||..:...||:|
Human    86 KEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQADSV-GLQVGDEIVRINGYSISSCTHEE 149

  Fly   228 AVRALKRSGRVVDLEVKFLREVTPYFRKASIISEVGWELQRAFLCPLGPGVPTSPPAP 285
            .:. |.|:.:.|.::|:.:..:..   |:|....:.|:....|:...| ||..|..:|
Human   150 VIN-LIRTKKTVSIKVRHIGLIPV---KSSPDEPLTWQYVDQFVSESG-GVRGSLGSP 202

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syn1NP_001262192.1 PH-like 30..>61 CDD:302622
PDZ_signaling 163..244 CDD:238492 28/80 (35%)
PHsplit_syntrophin <293..351 CDD:269960
USH1CXP_016872564.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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