DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and whrna

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	XP_002665968.3	Gene:	whrna / 100334777	ZFINID:	ZDB-GENE-091118-27	Length:	939	Species:	Danio rerio

Alignment Length:	311	Identity:	79/311 - (25%)
Similarity:	115/311 - (36%)	Gaps:	88/311 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PSGLRCGNMETRVRGAWYRVLVTLETDFLA--VSLDESCEAAQPSNDGQSTTLNGTLGSN----- 83
            |.|.:.|...:...||          :|.|  |:|..|.::...|:|| :.||...||.|
Zfish   117 PDGAQEGANSSPTHGA----------NFPASQVALRGSPDSISTSSDG-TATLIPLLGRNFLPEP 170

  Fly    84 -----------HSGGGGGGAG--GGGTGGGG------QNGTLPNSASL----QGMNIQDTELDGS 125
                       |....|.|..  ||...|.|      :.|:|.....|    |.|.:.|...|..
Zfish   171 PGEIRQVILKRHKSNEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRMGDQIMKVNDKVFDRV 235

  Fly   126 ASND-----NGDRDPCL--------------NNNNNAGDGGGMDMCDVPDHVANQK--------- 162
            ...|     .|.:..|:              |:.....|..|..:...||.:|..:
Zfish   236 THADAVKVLKGSKKLCMSVRSVGRIPGGYITNHVYTWVDPQGRSVSPPPDLLAEHRSATLRRSNS 300

  Fly   163 --------------RHVRIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKGLYVGDAIL 213
                          :.|.::..|...||:.|:||.|..:.|.|:.:.||.|| :..|:.|||.||
Zfish   301 QGRSHMQLLQDGDEKKVNLVLDDGRSLGLMIRGGAEYSLGIYITGVDRGSAA-ECGGIKVGDQIL 364

  Fly   214 TVNGEELRDATHDEAVRALKRSGRVVDLEVKFLREVTPYFRKASIISEVGW 264
            .|||.......||||||.||.|..:: :.||.:..: |:.|  :::.|..|
Zfish   365 EVNGRSFLSIPHDEAVRVLKSSHHLM-MTVKDVGRL-PHTR--TVVGETKW 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622	7/32 (22%)
		PDZ_signaling	163..244	CDD:238492	32/80 (40%)
		PHsplit_syntrophin	<293..351	CDD:269960
whrna	XP_002665968.3	HN_L-whirlin_R1_like	25..102	CDD:259822
		PDZ_signaling	174..255	CDD:238492	17/80 (21%)
		PDZ_signaling	314..394	CDD:238492	32/81 (40%)
		HN_L-whirlin_R2_like	459..538	CDD:259823
		PDZ_signaling	848..919	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810