DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syn1 and pdzd7a

DIOPT Version :9

Sequence 1:	NP_001262192.1	Gene:	Syn1 / 40424	FlyBaseID:	FBgn0037130	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001177686.1	Gene:	pdzd7a / 100332580	ZFINID:	ZDB-GENE-090313-191	Length:	954	Species:	Danio rerio

Alignment Length:	441	Identity:	102/441 - (23%)
Similarity:	162/441 - (36%)	Gaps:	131/441 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 NAGDGGGMDMCDVPDHVANQKRHVRIIKSDNNGLGISIKGGRENRMPILISKIFRGMAADQAKGL 206
            ||...||.|..|:  |.      :.:.||::..||.|::||.|:.:.|.:||:.....|:.| ||
Zfish    57 NAPVDGGDDSEDI--HT------ITVDKSEDGHLGFSVRGGSEHGLGIFVSKVEDDSTAEMA-GL 112

  Fly   207 YVGDAILTVNGEELRDATHDEAVRAL----------KRSGRVVDLEVKFLREVTPY---FRKASI 258
            .|||.::.|||..|...|...||:.|          :|.|:|..  :::.:|.|.:   ..:..:
Zfish   113 CVGDKLVEVNGISLESITMSSAVKVLTGNNRLRMVVRRVGKVPG--IRYSKEKTTWVDLIHRRMV 175

  Fly   259 ISEVGWELQRAFLCPLGPGVPTSPPAPKTTPRADTRYIPLQLTH----LARNLK---------YI 310
            :.|.|                 ..|:..::..|..|.:.|..|.    |..|::         |:
Zfish   176 VEESG-----------------RTPSEASSDGALRRIVHLYTTSDDYCLGFNIRGGKEFGLGIYV 223

  Fly   311 ---DPENRCFELHSPDGVH--SCILRA-ADSAEALVWFNALHSAMG-TSTQRALAEANR--ALTN 366
               ||..    |...:|:.  ..||.| ..|.|.:...||:..... |.....:.||.|  |...
Zfish   224 SKLDPGG----LAEQNGIKMGDQILAANGVSFEDITHSNAVEVLKSHTHVMLTIKEAGRYPAYKE 284

  Fly   367 LIGELKHIGWLSKRMSGGGSSGSAGGGAASG----GSGTSNSVVAG------------ELV---- 411
            ::.|   ..||:|..:||..|.|.|..:.|.    .|||..|.::|            |:|
Zfish   285 MVAE---YSWLNKLANGGQPSSSQGSDSYSSTSSLSSGTPVSSLSGLSQVTFPPAFGSEMVDVCI 346

  Fly   412 SPSGRSSSESSDESDKWLPIFVAVTEREFRIYESAPWSVEAWSRPLEIYALATTRLAG------- 469
            |...||...||              ||.....::.|...:..||...:.:..|:|:.|
Zfish   347 STEDRSRRPSS--------------ERIETAIQTDPQDPDTISRTSRVMSTETSRMVGETVLLKD 397

  Fly   470 ----------------AGNNSSLNGQQTTVFCVRCGTARGVLVYWLRSETH 504
                            ||:..:|:..:|.|........:.:    .||::|
Zfish   398 TVIRRGTAHSRTRTFSAGDKETLDSPKTAVLMALSKPRKAI----RRSQSH 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syn1	NP_001262192.1	PH-like	30..>61	CDD:302622
		PDZ_signaling	163..244	CDD:238492	29/90 (32%)
		PHsplit_syntrophin	<293..351	CDD:269960	17/77 (22%)
pdzd7a	NP_001177686.1	PDZ_signaling	69..149	CDD:238492	27/88 (31%)
		PDZ_signaling	194..274	CDD:238492	18/83 (22%)
		HN_PDZD7_like	568..645	CDD:259824
		PDZ_signaling	860..948	CDD:238492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910