Protein Alignment Rpb8 and POLR2H

DIOPT Version :9

• Sequence 1: NP_649352.1
• Gene: Rpb8 / 40415
• FlyBaseID: FBgn0037121
• Length: 149
• Species: Drosophila melanogaster
• Sequence 2: NP_001265627.1
• Gene: POLR2H / 5437
• HGNCID: 9195
• Length: 175
• Species: Homo sapiens
• Alignment Length: 134
• Identity: 89/134 - (66%)
• Similarity: 105/134 - (78%)
• Gaps: 10/134 - (7%)

  Fly     1 MAGVLFEDIFNVKDMDPEGKKFDRVSRLHCESESFKMDLILDINSWLYPMELGDKFRLVLATTLR 65
            |||:||||||:|||:|||||||||||||||||||||||||||:|..:||::||||||||:|:||.
Human     1 MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESESFKMDLILDVNIQIYPVDLGDKFRLVIASTLY 65

  Fly    66 EDGCPDSGEYNPMEHEGTRADSFEYVMYGKIYRIEGDEAHNEAS----RLSA------YVSFGGL 120
            |||..|.|||||.:...:|||.||||||||:|||||||...||:    ||.|      .::..||
Human    66 EDGTLDDGEYNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLLRLRAAEWQCSRITGWGL 130

  Fly   121 LMRL 124
            |.:|
Human   131 LFQL 134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpb8	NP_649352.1	RPOL8c	2..146	CDD:197821	88/133 (66%)
POLR2H	NP_001265627.1	RPOL8c	2..>106	CDD:197821	79/103 (77%)
		Non-specific ssDNA binding	16..40		23/23 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144442
Domainoid	1	1.000	226	1.000	Domainoid score	I2531
eggNOG	1	0.900	-	-		E1_KOG3400
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4540
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3341
Isobase	1	0.950	-	0	Normalized mean entropy	S652
OMA	1	1.010	-	-		QHG53918
OrthoDB	1	1.010	-	-		D1504067at2759
OrthoFinder	1	1.000	-	-		FOG0004425
OrthoInspector	1	1.000	-	-		oto91039
orthoMCL	1	0.900	-	-		OOG6_102056
Panther	1	1.100	-	-	LDO	PTHR10917
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1177
SonicParanoid	1	1.000	-	-		X3136
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750