Protein Alignment Polr2H and POLR2H

DIOPT Version :10

• Sequence 1: NP_649352.1
• Gene: Polr2H / 40415
• FlyBaseID: FBgn0037121
• Length: 149
• Species: Drosophila melanogaster
• Sequence 2: NP_001265627.1
• Gene: POLR2H / 5437
• HGNCID: 9195
• Length: 175
• Species: Homo sapiens
• Alignment Length: 134
• Identity: 89/134 - (66%)
• Similarity: 105/134 - (78%)
• Gaps: 10/134 - (7%)

  Fly     1 MAGVLFEDIFNVKDMDPEGKKFDRVSRLHCESESFKMDLILDINSWLYPMELGDKFRLVLATTLR 65
            |||:||||||:|||:|||||||||||||||||||||||||||:|..:||::||||||||:|:||.
Human     1 MAGILFEDIFDVKDIDPEGKKFDRVSRLHCESESFKMDLILDVNIQIYPVDLGDKFRLVIASTLY 65

  Fly    66 EDGCPDSGEYNPMEHEGTRADSFEYVMYGKIYRIEGDEAHNEAS----RLSA------YVSFGGL 120
            |||..|.|||||.:...:|||.||||||||:|||||||...||:    ||.|      .::..||
Human    66 EDGTLDDGEYNPTDDRPSRADQFEYVMYGKVYRIEGDETSTEAATRLLRLRAAEWQCSRITGWGL 130

  Fly   121 LMRL 124
            |.:|
Human   131 LFQL 134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr2H	NP_649352.1	RPOL8c	2..146	CDD:197821	88/133 (66%)
POLR2H	NP_001265627.1	RPOL8c	2..>106	CDD:197821	79/103 (77%)
		Non-specific ssDNA binding	16..40		23/23 (100%)