Protein Alignment CG11247 and ZAP1

DIOPT Version :10

• Sequence 1: NP_649351.2
• Gene: CG11247 / 40414
• FlyBaseID: FBgn0037120
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_012479.1
• Gene: ZAP1 / 853390
• SGDID: S000003592
• Length: 880
• Species: Saccharomyces cerevisiae
• Alignment Length: 453
• Identity: 119/453 - (26%)
• Similarity: 178/453 - (39%)
• Gaps: 110/453 - (24%)

  Fly    10 KEDAVSLLTDSGISLSSPPA-------------------ARESSPGPTLA------IKRRKSSLA 49
            |.:..:::.:||||.::..|                   .|..|..|:|.      .|.|:|...
Yeast   472 KPNRNNIVNNSGISAANTTADLTNNDLNDLISREYSYERFRNQSEPPSLPKVTHQNQKNRRSWPT 536

  Fly    50 SLRDACVDEEEDDGGEQDSKDDDYVQPQLKKSA----------RKGEPVKRKHHVCSQ-CSKEFG 103
            .      |.|..|....:......:.|.::.::          .|...:|.|...|.: ||..|
Yeast   537 K------DLESTDFSSLEDSLPSSISPPIQTTSTINFNWCFKEEKNNDLKCKWKECPESCSSLF- 594

  Fly   104 GKTDLQRHML---IHSDER----PHKC--KDCGKSYRQAVNLKNHITTAH--EHRKQFVCSQCPK 157
               |||||:|   :..|.:    |..|  :||........::.|||...|  ....||.   .|.
Yeast   595 ---DLQRHLLKDHVSQDFKHPMEPLACNWEDCDFLGDDTCSIVNHINCQHGINFDIQFA---NPD 653

  Fly   158 SF----ALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFS 218
            ||    ..||:   |..||.   |.|              |.|.||...           .|...
Yeast   654 SFLPGSISKEK---HHLLHC---PNP--------------QTHEVSKAD-----------GAPDM 687

  Fly   219 TNANLRVHMERHEQGMEHRCSI--CENQFANELALRAHINQEHHKLT----QFEC--EICHKMIE 275
            |:||...::...:|..:..|..  |...|::...|..|:...|  ||    :::|  ..||:...
Yeast   688 TSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVH--LTRGKSEYQCLWHDCHRTFP 750

  Fly   276 PDEDLATHMQRHTAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHI 340
            ..:.|..|::.|:..|.:.|:.|...|:.:.....|.|.|:||:||:|.||::.||.||.||:||
Yeast   751 QRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHI 815

  Fly   341 RKHTGEKPFRCQLCEDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVELQSHVEHCA 403
            |.||||||.:|::|...  |::.::|..|:|   ..||.|.|..|...|....:|.|....||
Yeast   816 RTHTGEKPLQCKICGKR--FNESSNLSKHIK---THQKKYKCSDCSKSFDDLGKLNSQKVKCA 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11247	NP_649351.2	COG5048	<88..247	CDD:227381	45/176 (26%)
		C2H2 Zn finger	95..115	CDD:275368	10/23 (43%)
		C2H2 Zn finger	123..144	CDD:275368	6/22 (27%)
		C2H2 Zn finger	152..172	CDD:275368	6/23 (26%)
		C2H2 Zn finger	180..200	CDD:275368	3/19 (16%)
		COG5048	<192..369	CDD:227381	56/184 (30%)
		C2H2 Zn finger	210..230	CDD:275370	4/19 (21%)
		C2H2 Zn finger	238..260	CDD:275371	5/23 (22%)
		C2H2 Zn finger	267..287	CDD:275368	5/21 (24%)
		C2H2 Zn finger	295..315	CDD:275368	5/19 (26%)
		C2H2 Zn finger	323..343	CDD:275368	12/19 (63%)
		C2H2 Zn finger	351..374	CDD:275368	6/22 (27%)
		C2H2 Zn finger	382..399	CDD:275368	5/16 (31%)
ZAP1	NP_012479.1	COG5048	292..761	CDD:227381	73/334 (22%)
		C2H2 Zn finger	743..762	CDD:275368	4/18 (22%)
		SUF4-like	766..>814	CDD:411020	20/47 (43%)
		C2H2 Zn finger	770..795	CDD:411020	8/24 (33%)
		C2H2 Zn finger	770..790	CDD:275368	5/19 (26%)
		C2H2 Zn finger	798..818	CDD:275368	12/19 (63%)
		zf-H2C2_2	810..834	CDD:463886	13/25 (52%)
		C2H2 Zn finger	826..846	CDD:275368	6/24 (25%)