DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11247 and ZNF442

DIOPT Version :9

Sequence 1:NP_001097659.1 Gene:CG11247 / 40414 FlyBaseID:FBgn0037120 Length:522 Species:Drosophila melanogaster
Sequence 2:XP_016882805.1 Gene:ZNF442 / 79973 HGNCID:20877 Length:635 Species:Homo sapiens


Alignment Length:363 Identity:108/363 - (29%)
Similarity:161/363 - (44%) Gaps:44/363 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 QLKKSARKGEPVKRKHHVCSQCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHIT 141
            ::.:....||    |.:.|.||.|.|...:...||...|:.|:|::||.|.|::....:...|..
Human   233 RMHERTHTGE----KPYECKQCCKAFPIYSSYLRHERTHTGEKPYECKHCSKAFPDYSSYVRHER 293

  Fly   142 TAHEHRKQFVCSQCPKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSH-----H 201
            | |...|.:.|.:|.::|::...||:|.|.|:|||||.|..|.|.|...|..|:||:.|     |
Human   294 T-HTGEKPYKCKRCGRAFSVSSSLRIHERTHTGEKPYECKQCGKAFHHLGSFQRHMIRHTGDGPH 357

  Fly   202 KTSI---------------------QQFNCTKCSASFSTNANLRVHMERHEQGMEHRCSICENQF 245
            |..|                     :.:.|.:|..:.|.:::.|.||..|.....|:|.:|...|
Human   358 KCKICGKGFDCPSSLQSHERTHTGEKPYECKQCGKALSHHSSFRSHMIMHTGDGPHKCKVCGKAF 422

  Fly   246 ANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATHMQRHTAVKTHVCEVCNTYFTQKSQYNV 310
            ......:.| .:.|.....:||:.|.|.......|..|...||..|.:.|: |...|.....:..
Human   423 IYPSVFQGH-ERTHTGEKPYECKECGKAFRISSSLRRHETTHTGEKPYKCK-CGKAFIDFYSFQN 485

  Fly   311 HMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCEDEVAFSQLAHLKNHMKKIHK 375
            |...||||:||:|:.|.:.|:..:.|..|.|.|..|||:.|:.|:.  |||...:||.| ::||.
Human   486 HETTHTGEKPYECKECGKAFSCFTYLSQHRRTHMAEKPYECKTCKK--AFSHFGNLKVH-ERIHT 547

  Fly   376 QQKPYMCEGCHDFFKIKVELQSHVE--------HCAKC 405
            .:|||.|:.|...|.....|..|..        .|.:|
Human   548 GEKPYECKECRKAFSWLTCLLRHERIHTGKKSYECQQC 585

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11247NP_001097659.1 COG5048 <88..247 CDD:227381 55/184 (30%)
C2H2 Zn finger 95..115 CDD:275368 7/19 (37%)
zf-H2C2_2 107..132 CDD:290200 9/24 (38%)
C2H2 Zn finger 123..144 CDD:275368 6/20 (30%)
C2H2 Zn finger 152..172 CDD:275368 7/19 (37%)
zf-H2C2_2 165..189 CDD:290200 14/23 (61%)
C2H2 Zn finger 180..200 CDD:275368 8/19 (42%)
COG5048 <192..369 CDD:227381 56/202 (28%)
C2H2 Zn finger 210..230 CDD:275370 6/19 (32%)
C2H2 Zn finger 238..260 CDD:275371 4/21 (19%)
C2H2 Zn finger 267..287 CDD:275368 5/19 (26%)
C2H2 Zn finger 295..315 CDD:275368 4/19 (21%)
zf-H2C2_2 309..332 CDD:290200 10/22 (45%)
C2H2 Zn finger 323..343 CDD:275368 6/19 (32%)
C2H2 Zn finger 351..374 CDD:275368 8/22 (36%)
C2H2 Zn finger 382..399 CDD:275368 4/16 (25%)
ZNF442XP_016882805.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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