back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11247 and ZNF726

DIOPT Version :9

Sequence 1:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001230967.1	Gene:	ZNF726 / 730087	HGNCID:	32462	Length:	616	Species:	Homo sapiens

Alignment Length:	366	Identity:	122/366 - (33%)
Similarity:	177/366 - (48%)	Gaps:	40/366 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SPGPTLAIKRRKSSLASLRDACVDEEEDDGGEQDSKDDD----YVQPQ---LKKSARKGEPVKRK 91
            |...||.|.:|..:                ||:..|.::    :.||.   :.|....||    |
Human   267 SQSSTLTIHKRIHT----------------GEKPCKCEECGKAFSQPSALTIHKRMHIGE----K 311

  Fly    92 HHVCSQCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITT---AHEHRKQFVCS 153
            .:.|.:|.|.|...:.|.||..:||.|:|:||::|.|::.|.    .|:||   .|...|.:.|.
Human   312 PYKCEECGKAFVWSSTLTRHKRLHSGEKPYKCEECAKAFSQF----GHLTTHRIIHTGEKPYKCE 372

  Fly   154 QCPKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFS 218
            :|.|:|.....|..|.|:|:|||||.|:.|.|.|.|...|.:|.:.|  |..:.:.|.:|..:|.
Human   373 ECGKAFIWPSTLTKHKRIHTGEKPYKCEECGKAFHRSSNLTKHKIIH--TGEKPYKCEECGKAFI 435

  Fly   219 TNANLRVHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATH 283
            .::||..|.:.|.:...::|..|...|:...||..| .:.|.....::||.|.|.......|..|
Human   436 WSSNLTEHKKIHTREKPYKCEECSKAFSRSSALTTH-KRMHTGEKPYKCEECGKAFSQSSTLTAH 499

  Fly   284 MQRHTAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKP 348
            ...||..|.:.||.|...|...|..:.|.|:||||:||:|..|.:||..||.|..|...||||||
Human   500 KIIHTGEKPYKCEECGKAFILSSTLSKHKRIHTGEKPYKCEECGKTFNQSSNLSTHKIIHTGEKP 564

  Fly   349 FRCQLCEDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFF 389
            ::|:.|..  ||::.::|..| |.||..:|||.|:.|...|
Human   565 YKCEECGK--AFNRSSNLSTH-KIIHTGEKPYKCDECGKSF 602

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.