DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11247 and Zfp808

DIOPT Version :9

Sequence 1:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001034328.2	Gene:	Zfp808 / 630579	MGIID:	3704127	Length:	753	Species:	Mus musculus

Alignment Length:	367	Identity:	128/367 - (34%)
Similarity:	198/367 - (53%)	Gaps:	23/367 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 LKKSARKGEPVKRKHHVCSQCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITT 142
            :.:....||    |.:.|:||.|.|.....||.|...|:.|:|:||..|.|::.:..:|:||| .
Mouse   402 IHRRTHTGE----KPYKCNQCDKAFSIHFPLQNHKRTHTGEKPYKCNQCDKAFSEKCHLQNHI-R 461

  Fly   143 AHEHRKQFVCSQCPKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSHHKTSIQQ 207
            .|...|.:.|:||.|:|:....|:.|.|:|:||||:.|:.|||.|::...||.|..:|  |..:.
Mouse   462 IHTGEKPYKCNQCDKAFSQYFSLQTHRRIHTGEKPFKCNQCDKAFSQYSTLQTHRRTH--TGEKP 524

  Fly   208 FNCTKCSASFSTNANLRVHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHK 272
            |.|.:|..:||.::.|:.|...|......:||.|:..|:....|:|| .:.|.....|:|:.|.|
Mouse   525 FKCNQCDKAFSKHSTLQSHRRTHSGEKPFKCSQCDKAFSQYNTLQAH-RRTHSGEKPFKCDQCDK 588

  Fly   273 MIEPDEDLATHMQRHTAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLK 337
            ......:|..|::.||..|.:.|..|:..|:|.:....|.|:||||:|::|..|.:.|:..|.|:
Mouse   589 AFSEKCNLQKHIRIHTGEKPYKCNQCDKAFSQYNTLQTHRRIHTGEKPFKCNQCDKAFSRHSTLQ 653

  Fly   338 LHIRKHTGEKPFRCQLCEDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVELQSHVE-H 401
            .|.|.|||||||:|..| |:| |||.::|:.| ::.|..:|||.|:.|...|.:|..||:||. |
Mouse   654 THRRTHTGEKPFKCNQC-DKV-FSQYSNLQTH-RRTHTGEKPYKCDQCDKAFSMKCNLQNHVRIH 715

  Fly   402 CAKCPVDGDKP-SGNQSEDAQILSVLRFNMAVVLKKISSAQK 442
                  .|:|| ..||.:.|    ..:::...:.:|..:.||
Mouse   716 ------TGEKPYKCNQCDKA----FFQYSNLHIHRKTHTGQK 747

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	57/158 (36%)
		C2H2 Zn finger	95..115	CDD:275368	8/19 (42%)
		zf-H2C2_2	107..132	CDD:290200	10/24 (42%)
		C2H2 Zn finger	123..144	CDD:275368	7/20 (35%)
		C2H2 Zn finger	152..172	CDD:275368	8/19 (42%)
		zf-H2C2_2	165..189	CDD:290200	13/23 (57%)
		C2H2 Zn finger	180..200	CDD:275368	8/19 (42%)
		COG5048	<192..369	CDD:227381	63/176 (36%)
		C2H2 Zn finger	210..230	CDD:275370	6/19 (32%)
		C2H2 Zn finger	238..260	CDD:275371	7/21 (33%)
		C2H2 Zn finger	267..287	CDD:275368	5/19 (26%)
		C2H2 Zn finger	295..315	CDD:275368	6/19 (32%)
		zf-H2C2_2	309..332	CDD:290200	10/22 (45%)
		C2H2 Zn finger	323..343	CDD:275368	7/19 (37%)
		C2H2 Zn finger	351..374	CDD:275368	9/22 (41%)
		C2H2 Zn finger	382..399	CDD:275368	6/16 (38%)
Zfp808	NP_001034328.2	KRAB	4..>45	CDD:214630
		KRAB	4..40	CDD:279668
		COG5048	<130..284	CDD:227381
		C2H2 Zn finger	135..155	CDD:275368
		C2H2 Zn finger	163..183	CDD:275368
		zf-H2C2_2	175..199	CDD:290200
		C2H2 Zn finger	191..211	CDD:275368
		zf-H2C2_2	203..227	CDD:290200
		C2H2 Zn finger	219..239	CDD:275368
		zf-H2C2_2	231..255	CDD:290200
		C2H2 Zn finger	247..267	CDD:275368
		zf-H2C2_2	259..284	CDD:290200
		C2H2 Zn finger	275..295	CDD:275368
		zf-H2C2_2	288..312	CDD:290200
		C2H2 Zn finger	303..323	CDD:275368
		zf-H2C2_2	315..340	CDD:290200
		COG5048	327..728	CDD:227381	124/342 (36%)
		C2H2 Zn finger	331..351	CDD:275368
		zf-H2C2_2	344..367	CDD:290200
		C2H2 Zn finger	359..379	CDD:275368
		zf-H2C2_2	371..396	CDD:290200
		C2H2 Zn finger	387..407	CDD:275368	0/4 (0%)
		C2H2 Zn finger	415..435	CDD:275368	8/19 (42%)
		zf-H2C2_2	428..451	CDD:290200	10/22 (45%)
		C2H2 Zn finger	443..463	CDD:275368	7/20 (35%)
		zf-H2C2_2	455..480	CDD:290200	11/25 (44%)
		C2H2 Zn finger	471..491	CDD:275368	8/19 (42%)
		zf-H2C2_2	483..508	CDD:290200	13/24 (54%)
		C2H2 Zn finger	499..519	CDD:275368	8/19 (42%)
		zf-H2C2_2	512..535	CDD:290200	8/24 (33%)
		C2H2 Zn finger	527..547	CDD:275368	6/19 (32%)
		zf-H2C2_2	540..564	CDD:290200	7/23 (30%)
		C2H2 Zn finger	555..575	CDD:275368	7/20 (35%)
		zf-H2C2_2	568..591	CDD:290200	8/23 (35%)
		C2H2 Zn finger	583..603	CDD:275368	5/19 (26%)
		zf-H2C2_2	595..620	CDD:290200	8/24 (33%)
		C2H2 Zn finger	611..631	CDD:275368	6/19 (32%)
		zf-H2C2_2	624..648	CDD:290200	10/23 (43%)
		C2H2 Zn finger	639..659	CDD:275368	7/19 (37%)
		zf-H2C2_2	652..676	CDD:290200	15/25 (60%)
		C2H2 Zn finger	667..687	CDD:275368	9/22 (41%)
		zf-H2C2_2	679..703	CDD:290200	8/24 (33%)
		C2H2 Zn finger	695..715	CDD:275368	8/19 (42%)
		zf-H2C2_2	707..730	CDD:290200	11/32 (34%)
		C2H2 Zn finger	723..743	CDD:275368	4/23 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000