DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11247 and Zfp607a

DIOPT Version :9

Sequence 1:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001019897.2	Gene:	Zfp607a / 545938	MGIID:	3584526	Length:	686	Species:	Mus musculus

Alignment Length:	510	Identity:	122/510 - (23%)
Similarity:	205/510 - (40%)	Gaps:	133/510 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RSVSKEDAVSLLTDSGISLSSPPAARESSPGPTLAIKRRKSSLASLRDACVDEEEDDGGEQDSKD 70
            |.:||.|.:.||              |....|.:|:|......:...:.|. |.|:...|..:.|
Mouse    56 RCISKPDLIVLL--------------EQEKEPWMAVKEETDRPSPDLELCY-EAENMSPENQTYD 105

  Fly    71 DDYVQPQLK-------------------------KSARKGEPVKR-------------------- 90
            .:..:.::|                         :|:::|:..::
Mouse   106 INLFKQRIKQFSKTFDLKICSFTSGPNYNTSKGLQSSQEGDDNQKITNKEEIPTHTCQTLAHNTE 170

  Fly    91 KHHVCSQCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITTAHEHRKQFVCSQC 155
            |.:.|.:|.|.||.::.|.:|..:|:.|:|::|::|||::|....|..| ..:|...:.|.|::|
Mouse   171 KAYECKECGKCFGCRSTLTQHQSVHAGEKPYECEECGKAFRLPQQLTRH-QKSHSGERPFECNEC 234

  Fly   156 PKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQH------------------------ 196
            .|:|.|.:.|:.|..:|:.|||:.|::|.|.|.|...|.:|
Mouse   235 GKAFHLPDLLKYHKVIHTDEKPFECEVCGKSFKRVSHLVEHRTIHAGVKPYECSECAKAFKRRSY 299

  Fly   197 MVSHHK------------------------------TSIQQFNCTKCSASFSTNANLRVHMERHE 231
            ::.|.|                              |..:.|.|..|...||..:.|..|...|.
Mouse   300 LMQHQKIHSGERPFQCKDCGKSFIVLAQLTRHQNIHTEDKSFECKHCGKIFSCGSFLLRHQSIHT 364

  Fly   232 QGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATHMQRHTAVKTHVCE 296
            ......|::|...|..::.|..| .:.|.....|||::|.......:.|:.|.:.||.||.:.|:
Mouse   365 NEKPFECNVCGKAFRLQVYLSEH-RKTHTDERPFECKLCGSAFRRKDQLSEHQKIHTNVKPYQCK 428

  Fly   297 VCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLCEDEVAFS 361
            .|...|.:||.:..|..:|:.::|:.|:.|.:.|..::.|..|.:.|:||:||.|:.|..  ||.
Mouse   429 ECGNLFRRKSSFIEHQSIHSEKKPFNCKDCGKVFRLNTHLMRHQKSHSGERPFECKECGK--AFH 491

  Fly   362 QLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVELQSHVEH-----------CAKC 405
            ..:.|..| |.:|..|||:.||.|...||   .:.|.:||           |.:|
Mouse   492 LPSQLTYH-KTVHTNQKPFACEECGKSFK---HVSSLIEHRVIHAGLKPYECGEC 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	52/232 (22%)
		C2H2 Zn finger	95..115	CDD:275368	7/19 (37%)
		zf-H2C2_2	107..132	CDD:290200	9/24 (38%)
		C2H2 Zn finger	123..144	CDD:275368	7/20 (35%)
		C2H2 Zn finger	152..172	CDD:275368	7/19 (37%)
		zf-H2C2_2	165..189	CDD:290200	10/23 (43%)
		C2H2 Zn finger	180..200	CDD:275368	7/43 (16%)
		COG5048	<192..369	CDD:227381	52/230 (23%)
		C2H2 Zn finger	210..230	CDD:275370	6/19 (32%)
		C2H2 Zn finger	238..260	CDD:275371	5/21 (24%)
		C2H2 Zn finger	267..287	CDD:275368	4/19 (21%)
		C2H2 Zn finger	295..315	CDD:275368	6/19 (32%)
		zf-H2C2_2	309..332	CDD:290200	6/22 (27%)
		C2H2 Zn finger	323..343	CDD:275368	5/19 (26%)
		C2H2 Zn finger	351..374	CDD:275368	7/22 (32%)
		C2H2 Zn finger	382..399	CDD:275368	6/16 (38%)
Zfp607a	NP_001019897.2	KRAB	14..75	CDD:214630	8/32 (25%)
		C2H2 Zn finger	175..195	CDD:275368	7/19 (37%)
		C2H2 Zn finger	203..223	CDD:275368	7/20 (35%)
		COG5048	227..572	CDD:227381	85/323 (26%)
		C2H2 Zn finger	231..251	CDD:275368	7/19 (37%)
		C2H2 Zn finger	259..279	CDD:275368	7/19 (37%)
		C2H2 Zn finger	287..307	CDD:275368	2/19 (11%)
		C2H2 Zn finger	315..335	CDD:275368	0/19 (0%)
		C2H2 Zn finger	343..363	CDD:275368	6/19 (32%)
		C2H2 Zn finger	371..391	CDD:275368	5/20 (25%)
		C2H2 Zn finger	399..419	CDD:275368	4/19 (21%)
		C2H2 Zn finger	427..447	CDD:275368	6/19 (32%)
		C2H2 Zn finger	455..475	CDD:275368	5/19 (26%)
		C2H2 Zn finger	483..503	CDD:275368	7/22 (32%)
		C2H2 Zn finger	511..531	CDD:275368	8/22 (36%)
		C2H2 Zn finger	539..559	CDD:275368	2/4 (50%)
		C2H2 Zn finger	567..587	CDD:275368
		C2H2 Zn finger	595..615	CDD:275368
		zf-H2C2_2	608..632	CDD:404364
		C2H2 Zn finger	623..643	CDD:275368
		zf-H2C2_2	635..658	CDD:404364
		C2H2 Zn finger	651..671	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000