DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11247 and CG10348

DIOPT Version :9

Sequence 1:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	48/184 - (26%)
Similarity:	81/184 - (44%)	Gaps:	53/184 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 HVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRK-HTGEKPFRCQLCED 356
            :.|:.|...|.:.:....|:|.||||:||:|:.|.::|:.||.|:.|:|. |..|:||:|::||.
  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375

  Fly   357 EVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVELQSHVE---HCAK--CPVDGDKPSGNQ 416
              .|.|..:|..|:||             |:...:.:...|.|.   ||.:  |.        |.
  Fly   376 --CFGQQTNLDRHLKK-------------HESDAVSLSALSGVSERMHCIRRFCE--------NP 417

  Fly   417 SEDAQILSVLRFNMAVVLKKISSAQKLRQLGYEKRLIDNVIIASLKLAQRQSHD 470
            :|::....:..|     :.|::..|:.:|                   |:|.||
  Fly   418 TEESYFEEIRSF-----MGKVTQQQQQQQ-------------------QQQQHD 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381
		C2H2 Zn finger	95..115	CDD:275368
		zf-H2C2_2	107..132	CDD:290200
		C2H2 Zn finger	123..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		zf-H2C2_2	165..189	CDD:290200
		C2H2 Zn finger	180..200	CDD:275368
		COG5048	<192..369	CDD:227381	29/76 (38%)
		C2H2 Zn finger	210..230	CDD:275370
		C2H2 Zn finger	238..260	CDD:275371
		C2H2 Zn finger	267..287	CDD:275368
		C2H2 Zn finger	295..315	CDD:275368	5/19 (26%)
		zf-H2C2_2	309..332	CDD:290200	11/22 (50%)
		C2H2 Zn finger	323..343	CDD:275368	8/20 (40%)
		C2H2 Zn finger	351..374	CDD:275368	9/22 (41%)
		C2H2 Zn finger	382..399	CDD:275368	2/16 (13%)
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	19/51 (37%)
		zf-C2H2	311..333	CDD:278523	5/21 (24%)
		C2H2 Zn finger	313..333	CDD:275368	5/19 (26%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	10/25 (40%)
		zf-C2H2	368..390	CDD:278523	10/36 (28%)
		C2H2 Zn finger	370..390	CDD:275368	9/34 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24393
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010