DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11247 and Zfp184

DIOPT Version :9

Sequence 1:	NP_001097659.1	Gene:	CG11247 / 40414	FlyBaseID:	FBgn0037120	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_898835.1	Gene:	Zfp184 / 193452	MGIID:	1922244	Length:	737	Species:	Mus musculus

Alignment Length:	362	Identity:	124/362 - (34%)
Similarity:	178/362 - (49%)	Gaps:	24/362 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KHHVCSQCSKEFGGKTDLQRHMLIHSDERPHKCKDCGKSYRQAVNLKNHITTAHEHRKQFVCSQC 155
            |.:.|::|.|.|.|.:...||.:||:.|:|::|.:|||::.|..||..|..| |...|.:.|::|
Mouse   367 KTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKT-HTGEKPYDCAEC 430

  Fly   156 PKSFALKERLRLHMRLHSGEKPYPCDLCDKKFARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTN 220
            .|:|:....|..|:::|:|||||.|..|.|.|:....|.||...|  |..:.|.|::|..:||..
Mouse   431 GKAFSYWSSLAQHLKIHTGEKPYKCSDCGKAFSYCSSLTQHRRIH--TREKPFECSECGKAFSYL 493

  Fly   221 ANLRVHMERHEQGMEHRCSICENQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATHMQ 285
            :||..|.:.|.|...:.|..|...|....:|..| .:.|.....::|..|.|.......|..|.:
Mouse   494 SNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKH-ERIHTGEKPYQCHECGKTFSYGSSLIQHKK 557

  Fly   286 RHTAVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFR 350
            .||..:.:.|..|...|.||.....|.|:|||.:||.|..|.:||.|.|.|..|.:.||.|||::
Mouse   558 IHTGERPYKCNECGRAFNQKIHLTQHKRIHTGAKPYACPKCGKTFRHCSSLAQHQKTHTEEKPYQ 622

  Fly   351 CQLCEDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVELQSHVEHCAKCPVDGDKPSGN 415
            |..||.  .|||.:.|..| ::||..:|||.|..|...|...|.|..|     :....|:||..:
Mouse   623 CNKCEK--TFSQNSRLTQH-QRIHTGEKPYKCSECDKCFTGSVHLTEH-----RSTHTGEKPYNS 679

  Fly   416 QSEDAQILSVLRFNMAVVL---KKISSAQKLRQLGYE 449
            :....       |:.:..|   :||.|.:||  ||.|
Mouse   680 ECPQT-------FSQSTYLTQHQKIHSGEKL--LGCE 707

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11247	NP_001097659.1	COG5048	<88..247	CDD:227381	57/155 (37%)
		C2H2 Zn finger	95..115	CDD:275368	7/19 (37%)
		zf-H2C2_2	107..132	CDD:290200	10/24 (42%)
		C2H2 Zn finger	123..144	CDD:275368	9/20 (45%)
		C2H2 Zn finger	152..172	CDD:275368	6/19 (32%)
		zf-H2C2_2	165..189	CDD:290200	12/23 (52%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		COG5048	<192..369	CDD:227381	60/176 (34%)
		C2H2 Zn finger	210..230	CDD:275370	7/19 (37%)
		C2H2 Zn finger	238..260	CDD:275371	5/21 (24%)
		C2H2 Zn finger	267..287	CDD:275368	5/19 (26%)
		C2H2 Zn finger	295..315	CDD:275368	7/19 (37%)
		zf-H2C2_2	309..332	CDD:290200	11/22 (50%)
		C2H2 Zn finger	323..343	CDD:275368	8/19 (42%)
		C2H2 Zn finger	351..374	CDD:275368	8/22 (36%)
		C2H2 Zn finger	382..399	CDD:275368	5/16 (31%)
Zfp184	NP_898835.1	KRAB	28..88	CDD:214630
		COG5048	163..634	CDD:227381	98/272 (36%)
		C2H2 Zn finger	203..223	CDD:275368
		C2H2 Zn finger	231..251	CDD:275368
		C2H2 Zn finger	259..279	CDD:275368
		C2H2 Zn finger	287..307	CDD:275368
		C2H2 Zn finger	315..335	CDD:275368
		C2H2 Zn finger	343..363	CDD:275368
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	399..419	CDD:275368	9/20 (45%)
		C2H2 Zn finger	427..447	CDD:275368	6/19 (32%)
		C2H2 Zn finger	455..475	CDD:275368	7/19 (37%)
		C2H2 Zn finger	483..503	CDD:275368	7/19 (37%)
		C2H2 Zn finger	511..531	CDD:275368	5/20 (25%)
		C2H2 Zn finger	539..559	CDD:275368	5/19 (26%)
		C2H2 Zn finger	567..587	CDD:275368	7/19 (37%)
		C2H2 Zn finger	595..615	CDD:275368	8/19 (42%)
		C2H2 Zn finger	623..643	CDD:275368	8/22 (36%)
		zf-H2C2_2	635..659	CDD:372612	9/24 (38%)
		C2H2 Zn finger	651..671	CDD:275368	6/24 (25%)
		C2H2 Zn finger	679..698	CDD:275368	3/25 (12%)
		C2H2 Zn finger	706..726	CDD:275368	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000