Protein Alignment CG11247 and ZNF497

DIOPT Version :10

• Sequence 1: NP_649351.2
• Gene: CG11247 / 40414
• FlyBaseID: FBgn0037120
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_940860.2
• Gene: ZNF497 / 162968
• HGNCID: 23714
• Length: 498
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 131/449 - (29%)
• Similarity: 186/449 - (41%)
• Gaps: 84/449 - (18%)

  Fly    25 SSPPAARESSPGPTLAIKRRKSSLASLRDACVDEE-------------EDDGGEQDSKDDDYVQP 76
            :|....||:..|     :|::::|.:     .||:             .|..|.:....|..::|
Human    43 NSTEVPREAGDG-----QRQQATLGA-----ADEQGGPGRELGPADGGRDGAGPRSEPADRALRP 97

  Fly    77 Q---LKKSARKGEPVK-----------------RKHHVCSQCSKEFGGKTDLQRHMLIHSDERPH 121
            .   .:...|.||..|                 .|.:.|.:|.|.|...::|.:|..|||.|:|:
Human    98 SPLPEEPGCRCGECGKAFSQGSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPY 162

  Fly   122 KCKDCGKSYRQAVNLKNHITTAHEHRKQFVCSQCPKSFALKERLRLHMRLHSGEKPYPCDLCDKK 186
            .|::|||::|....|.:|..| |...|.|.|..|.|||.....|..|.|.|:|||||.|..|.|.
Human   163 ACRECGKAFRAHSQLIHHQET-HSGLKPFRCPDCGKSFGRSTTLVQHRRTHTGEKPYECPECGKA 226

  Fly   187 FARGGQLQQHMVSHHKTSIQQFNCTKCSASFSTNANLRVHMERHEQGMEHRCSICENQFANELAL 251
            |:......:|...|  |..:...|..|..:||.::||..|::.|.....|.|..|...|.....|
Human   227 FSWNSNFLEHRRVH--TGARPHACRDCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGL 289

  Fly   252 RAHIN-----------------QEHHKLTQ----------FECEICHKMIEPDEDLATHMQRHTA 289
            |.|..                 :|..:|.|          |||..|.:.......||.|.:.||.
Human   290 RQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAFVMGSYLAEHRRVHTG 354

  Fly   290 VKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQTFAHSSVLKLHIRKHTGEKPFRCQLC 354
            .|.|.|..|...|:|:|....|.|.|:|.:|:.|..|.:.|..||.|..|...||||:||.|..|
Human   355 EKPHACAQCGKAFSQRSNLLSHRRTHSGAKPFACADCGKAFRGSSGLAHHRLSHTGERPFACAEC 419

  Fly   355 EDEVAFSQLAHLKNHMKKIHKQQKPYMCEGCHDFFKIKVELQSHVE-H-------CAKC 405
            ..  ||...:.|:.| :::|..::|::|..|...|..|.||.||.. |       |.:|
Human   420 GK--AFRGSSELRQH-QRLHSGERPFVCAHCSKAFVRKSELLSHRRTHTGERPYACGEC 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11247	NP_649351.2	COG5048	<88..247	CDD:227381	57/175 (33%)
		C2H2 Zn finger	95..115	CDD:275368	6/19 (32%)
		C2H2 Zn finger	123..144	CDD:275368	8/20 (40%)
		C2H2 Zn finger	152..172	CDD:275368	8/19 (42%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		COG5048	<192..369	CDD:227381	60/203 (30%)
		C2H2 Zn finger	210..230	CDD:275370	7/19 (37%)
		C2H2 Zn finger	238..260	CDD:275371	7/38 (18%)
		C2H2 Zn finger	267..287	CDD:275368	5/19 (26%)
		C2H2 Zn finger	295..315	CDD:275368	7/19 (37%)
		C2H2 Zn finger	323..343	CDD:275368	7/19 (37%)
		C2H2 Zn finger	351..374	CDD:275368	6/22 (27%)
		C2H2 Zn finger	382..399	CDD:275368	7/16 (44%)
ZNF497	NP_940860.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..104		12/70 (17%)
		COG5048	107..492	CDD:227381	119/375 (32%)
		C2H2 Zn finger	108..128	CDD:275368	3/19 (16%)
		C2H2 Zn finger	136..156	CDD:275368	6/19 (32%)
		C2H2 Zn finger	164..184	CDD:275368	8/20 (40%)
		C2H2 Zn finger	192..212	CDD:275368	8/19 (42%)
		C2H2 Zn finger	220..240	CDD:275368	5/19 (26%)
		C2H2 Zn finger	248..268	CDD:275368	7/19 (37%)
		C2H2 Zn finger	276..296	CDD:275368	6/19 (32%)
		C2H2 Zn finger	304..324	CDD:275368	3/19 (16%)
		C2H2 Zn finger	332..352	CDD:275368	5/19 (26%)
		C2H2 Zn finger	360..380	CDD:275368	7/19 (37%)
		C2H2 Zn finger	388..408	CDD:275368	7/19 (37%)
		C2H2 Zn finger	416..436	CDD:275368	6/22 (27%)
		C2H2 Zn finger	444..464	CDD:275368	8/19 (42%)
		C2H2 Zn finger	472..492	CDD:275368	2/4 (50%)