Protein Alignment Als2 and AT3G23270

DIOPT Version :10

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_001327882.1
• Gene: AT3G23270 / 821906
• AraportID: AT3G23270
• Length: 1054
• Species: Arabidopsis thaliana
• Alignment Length: 1410
• Identity: 249/1410 - (17%)
• Similarity: 403/1410 - (28%)
• Gaps: 569/1410 - (40%)

  Fly    21 IYHE------------GRELQLHWR-GLPPLQRFPAS-----RICSNAGGE--LLLLTTDH---- 61
            ||||            |.:|..:.| |.|..:.|..|     .|..:.|.|  |.|.....
plant     9 IYHERDVDQALVVLKKGTQLLKYSRKGKPKFRAFRLSPDEKTLIWFSRGEEKGLKLFEVSRIVPG 73

  Fly    62 ---ALYSAKLQANREHMDLQLL---RTDVVDMDFCSGSQELFVVLTNGSVQRQATGSGRDVGHPH 120
               |::...|:..::|:...||   |...:|: .|                       :|.....
plant    74 QRTAVFKRFLRPEKDHLSFSLLYNNRERSLDL-IC-----------------------KDKAETE 114

  Fly   121 AWQTLGFDPLELHAEGVRIRRVCCSAQGVVFVGASGETYVMGSCGEVFKAEQQPRHMRLYEEGKE 185
            .|    |..|:...|..|.||    |:..:......:|:.:|.....|.....||       |:.
plant   115 VW----FAALKFLIEKSRNRR----ARSEIPEIHDSDTFSVGRQSIDFVPSNIPR-------GRT 164

  Fly   186 LLDLAAGNEHFV-----MLVAPYNLADDALQLSVASAKEEPEDERASVKSISSGHSERSVAANTR 245
            .:||...|...|     .::.|   :.|..::||           :|..|.|||.|      ...
plant   165 SIDLGYQNNSDVGYERGNMLRP---STDGFRISV-----------SSTPSCSSGGS------GPD 209

  Fly   246 HLLHQGYALLHTQLFTFGASNNGLLGSGDHIRRANVMRLQKLDS---MGVCSIAAGLEHTVARTL 307
            .:...|...:..:::|.|...:|.  :.:...:.:|:..:.|:|   :.|..|..|:.|....|.
plant   210 DIESLGDVYVWGEVWTEGILPDGT--ASNETVKTDVLTPRPLESNVVLDVHQIVCGVRHVALVTR 272

  Fly   308 DGRLYHWGLNNHSQLGE----DVSSPMEITITENTAALPIEQNSALEATCGDYHTLLLNASGQIH 368
            .|.::.||.....:||.    |:|.|   .:.|..|...|:     ...||:|||.:::.||.:.
plant   273 QGEVFTWGEEVGGRLGHGIQVDISRP---KLVEFLALTNID-----FVACGEYHTCVVSTSGDLF 329

  Fly   369 SLQPAPPMRHLQQSSTYAQTLLQLQLGAAWPRQLRLLMCSGGYTLQNQRQFQRQYHYYLSHLQSQ 433
            |                            |           |..:.|..
plant   330 S----------------------------W-----------GDGIHNVG---------------- 339

  Fly   434 LQLLLKHRQAVQTLEIWQRQSALEPLSALGPLLINWERILCLLVATLHSLEGFYRADFVQPADLL 498
               ||.|...:..   |..:....||..|        ::|.:...|.||.
plant   340 ---LLGHGSDISH---WIPKRVSGPLEGL--------QVLSVACGTWHSA--------------- 375

  Fly   499 FICHYKEYIDLFDGYTKAYCDVFSVNG----FGEAVVAITGLSSPLAELNEESYVTRLFQQPFSI 559
                                 :.:.||    ||:....:.|..      |.||
plant   376 ---------------------LATANGKLFTFGDGAFGVLGHG------NRES------------ 401

  Fly   560 YQLFVQFMELLVRTQSEYGEHRVAWSEFARHSCISQELAVNTKDFWSSNDRNPRIVQFRGRHRRV 624
                                  |::                           |:.||
plant   402 ----------------------VSY---------------------------PKEVQ-------- 409

  Fly   625 ILTSALVPLKLVTSGISRSSNSFILFSDFLCQVSGNSLYSYPLTTLWVWTEGDSLRLTTPEK-SF 688
                :|..||.|....|      |..:..:.:|.|.:..|.....|:.|.:||..||....| ::
plant   410 ----SLNGLKTVKVACS------IWHTAAIVEVMGQTATSMSSRKLFTWGDGDKNRLGHGNKETY 464

  Fly   689 LVSTRSQEMRKVWLDQLQSSIIASLGKPLGSPVPSYR----STGYEFSREHPKFSRVKACGTWRK 749
            |:.|            ..||:|            .|.    :.|:.|:........|...|
plant   465 LLPT------------CVSSLI------------DYNFHKIACGHTFTVALTTSGHVFTMG---- 501

  Fly   750 GVLHGNCYLEYPDGSVYC-------GELQHGIIEGFGKMVIPTTGLYV---GNFKGGRFHGHG-- 802
            |..||.......||.:.|       ||....|..|...:.:.|:...|   |....||. |||
plant   502 GTAHGQLGNSISDGKLPCLVQDRLVGEFVEEIACGAHHVAVLTSRSEVFTWGKGANGRL-GHGDT 565

  Fly   803 ----------------VYEMHCKDSPESEV--------YEGNFCEGLFHGHGVMRNNRYIY-VGE 842
                            |..:.|..:..|.:        .:.:.|.|.....|..|.....| .|.
plant   566 EDKRTPTLVEALRDRHVKSLSCGSNFTSSICIHKWVSGADQSICSGCRQAFGFTRKRHNCYNCGL 630

  Fly   843 YQANARSG----------------------YGVIEDLVSGDKYMGMFADNKRSGIGSCITNRGDY 885
            ...:|.|.                      |..::...||          ..|.:...:...|..
plant   631 VHCHACSSKKALKAALAPTPGKPHRVCDACYSKLKAAESG----------YSSNVNRNVATPGRS 685

  Fly   886 FEGSFSGDDLT--GSGVAVFENDYYYEGELTLLGPNGRGEYYMPSGDACGGSGAMGTGE-----F 943
            .:||...|..|  .|.|.:..|      :.:::..:..|  :.|.......|......:     |
plant   686 IDGSVRTDRETTRSSKVLLSAN------KNSVMSSSRPG--FTPESSNARASQVPSLQQLKDIAF 742

  Fly   944 DDTCELIGNKMFGQLSGTWDTVRIQAGELVLNRRFPKYP------------------SSLGRQVV 990
            ..:...|.|.....::.|....|    .||:....|..|                  |...|.|:
plant   743 PSSLSAIQNAFKPVVAPTTTPPR----TLVIGPSSPSPPPPPRSSSPYARRPSPPRTSGFSRSVI 803

  Fly   991 DHNRKWRSLFNNFESDLANCTASTSSSGGNQSAGT----LRKSSKPTLSTAQIWNCIAVYMSKQR 1051
            |..||...:.|...:.|.:...:......||  ||    .:|::|..              |:..
plant   804 DSLRKTNEVMNQEMTKLHSQVKNLKQRCNNQ--GTEIERFQKAAKDA--------------SELA 852

  Fly  1052 AREGTKPGNYFNNILLSLPLPQKTSSPLAKARTTTSALSKLQTEAASALDFLGFPPRRIQSQ--E 1114
            ||:.                        :|.:..|.||..:..:.....:.|  ||...:|:  |
plant   853 ARQS------------------------SKHKAATEALKSVAEQLKELKEKL--PPEVSESEAFE 891

  Fly  1115 ALNSKPGGLQRADSLISMGHNTSRDLDNSSLASFQLDQSLMNSTVNGDESSTFNESFSKLSHNNN 1179
            ::||      :|::.:    |.::..:.|.|            |.:|.|..|:.::..::..|:
plant   892 SINS------QAEAYL----NANKVSETSPL------------TTSGQEQETYQKTEEQVPSNS- 933

  Fly  1180 NSISKHMNNIDCSITSTTSTTSAVLDQVPSFGMALVLTEQDVTSIRLYLEQAFKDRHHP-LYVLN 1243
                        |||.|:|::.|     ||         .:.:|.|:..::: |::..| :||..
plant   934 ------------SITETSSSSRA-----PS---------TEASSSRISGKES-KEQFEPGVYVTY 971

  Fly  1244 ERIANCFHYSYGYWKVKPTPILAKQAMREWESISRRIYRFVRKMF 1288
            |...|                        ...|.||: ||.:|.|
plant   972 EVDMN------------------------GNKIFRRV-RFSKKRF 991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	ATS1	<238..>367	CDD:444065	30/135 (22%)
		PH-like	616..715	CDD:473070	22/99 (22%)
		COG4642	<745..890	CDD:443680	36/203 (18%)
		PLN03185	835..>962	CDD:215619	22/156 (14%)
		VPS9	1373..1479	CDD:460489
AT3G23270	NP_001327882.1	PH_PLC_plant-like	13..124	CDD:270171	24/138 (17%)
		ATS1	215..572	CDD:444065	101/585 (17%)
		FYVE	598..665	CDD:214499	9/66 (14%)
		COG1340	<803..914	CDD:440951	29/174 (17%)
		BRX_N	854..890	CDD:404581	9/61 (15%)
		BRX	957..1011	CDD:429960	13/61 (21%)