DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Als2 and Morn3

DIOPT Version :9

Sequence 1:	NP_649347.1	Gene:	Als2 / 40410	FlyBaseID:	FBgn0037116	Length:	1486	Species:	Drosophila melanogaster
Sequence 2:	XP_038946061.1	Gene:	Morn3 / 687615	RGDID:	1583091	Length:	269	Species:	Rattus norvegicus

Alignment Length:	210	Identity:	55/210 - (26%)
Similarity:	85/210 - (40%)	Gaps:	44/210 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   743 ACGTWRKGVLHGNCYLEYPDGS-----------------VYCGELQHGIIEGFGKMVIPTTG-LY 789
            |.||||          .:|:..                 ::.|..|.....|....|....| .|
  Rat    12 AAGTWR----------TFPEKQRNAVSMPVTKCPRKSEPLWKGWDQKAQKNGLRHQVFAVNGDHY 66

  Fly   790 VGNFKGGRFHGHG--VYEMHCKDSPESEVYEGNFCEGLFHGHGVMRNN-------RYIYVGEYQA 845
            ||.:||...||.|  |::.      ...:|||::..|...|:|::.:.       :.:|.|.::.
  Rat    67 VGEWKGNLKHGKGTQVWKQ------SGAMYEGDWKFGKRDGYGILSHPDPETGKLKRVYSGWWKG 125

  Fly   846 NARSGYGVIEDLVSGDKYMGMFADNKRSGIGSCITNRGDYFEGSFSGDDLTGSGVAVFENDYYYE 910
            :.:|||| |:.....:.|.|.:..|:|||.|....|.||.:||.:..|...|.|:...:|...||
  Rat   126 DKKSGYG-IQFFGPKEYYEGEWCSNQRSGWGRMYYNNGDIYEGQWKNDKPDGEGMLRLKNGNRYE 189

  Fly   911 GELTLLGPNGRGEYY 925
            |.......||.|.::
  Rat   190 GSWERGMKNGHGRFF 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	RCC1	258..304	CDD:278826
		RCC1_2	292..321	CDD:290274
		RCC1	308..361	CDD:278826
		PH-like	616..715	CDD:302622
		VPS9	1373..1479	CDD:280383
Morn3	XP_038946061.1	PLN03185	62..>216	CDD:215619	45/150 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900