Protein Alignment Als2 and Rcc1

DIOPT Version :10

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: XP_006239135.1
• Gene: Rcc1 / 682908
• RGDID: 1592835
• Length: 434
• Species: Rattus norvegicus
• Alignment Length: 327
• Identity: 75/327 - (22%)
• Similarity: 119/327 - (36%)
• Gaps: 84/327 - (25%)

  Fly    91 SGSQELFVVLTNGSVQRQATGSGRDVGHPHAWQTLGFDPLE-------------LHAEGVRIRRV 142
            |.:.|..:|||        .|.| |||.    ..||...||             :.||...:..|
  Rat    42 SHNTEPGLVLT--------LGQG-DVGQ----LGLGESVLERKKPALVPLLQDVVQAEAGGMHTV 93

  Fly   143 CCSAQGVVFVGASGETYVMGSCGEVFKAEQQPRHMRLYEEGKELLDLAAGNEHFVMLVAPYNLAD 207
            |.|..|.|:.....:...:|....|..:|..|..:.|.|   :::.::||:.|...      |.:
  Rat    94 CLSQSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQE---KVVQVSAGDSHTAA------LTE 149

  Fly   208 DALQLSVASAKE--------EPEDERASVKSISSGHSERSVAANTRHLLHQGYALLHT--QLFTF 262
            |.......|.::        ||..:......:........||:...||:     :|.|  .|:|.
  Rat   150 DGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDTQVVKVASGNDHLV-----MLTTDGDLYTL 209

  Fly   263 GASNNGLL----------GSGDHIRRANVMRLQKLDSMGV----------CSIAAGLEHTVARTL 307
            |....|.|          |....:.|..|.|...|.|.|.          |    |...|.|.:.
  Rat   210 GCGEQGQLGRVPELFANRGGRQGLERLLVPRCVLLKSRGTRGRVRFQDAFC----GAYFTFAISR 270

  Fly   308 DGRLYHWGLNNHSQLGEDVSS----PMEITITENTAALPIEQNSALEATCGDYHTLLLNASGQIH 368
            :|.:|.:||:|:.|||...:.    |..:|..:|:.      .|.:..:.|.:||:.:::.|:.:
  Rat   271 EGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFKNST------KSWVGFSGGQHHTVCMDSEGKAY 329

  Fly   369 SL 370
            ||
  Rat   330 SL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	ATS1	<238..>367	CDD:444065	38/154 (25%)
		PH-like	616..715	CDD:473070
		COG4642	<745..890	CDD:443680
		PLN03185	835..>962	CDD:215619
		VPS9	1373..1479	CDD:460489
Rcc1	XP_006239135.1	ATS1	45..402	CDD:444065	74/324 (23%)