Protein Alignment Als2 and jph1b

DIOPT Version :10

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_001037813.1
• Gene: jph1b / 556485
• ZFINID: ZDB-GENE-060616-389
• Length: 673
• Species: Danio rerio
• Alignment Length: 453
• Identity: 101/453 - (22%)
• Similarity: 163/453 - (35%)
• Gaps: 117/453 - (25%)

  Fly   759 EYPDGSVYCGELQHGIIEGFGKMVIPT-TGLYVGNFKGGRFHGHGVYEMHCKDSPESEVYEGNFC 822
            ::.||..:||..:.|...|.|....|. .|.|.|::..| |...|||..     |....|:|.:.
Zfish     7 DFDDGGTFCGGWEDGKAHGHGICTGPKGQGEYSGSWSNG-FEVVGVYTW-----PSGNTYKGYWA 65

  Fly   823 EGLFHGHGVMRNNRYIYVGEYQANARSGYGVIEDLVSGDKYMGMFADNKRSGIGSCITNRGDYFE 887
            :|..||.||....|::|.||:....:..|||.:.|.:..:|.|.:::..:.|.|......|..::
Zfish    66 QGKRHGLGVESKGRWLYRGEWSHGFKGRYGVRQSLNTPARYEGTWSNGLQDGYGVETYGDGGTYQ 130

  Fly   888 GSFSGDDLTGSGVAVFENDYYYEGELTLLGPNGRGEYYMPSGDACGGSGAMGTGEFDDTCELIGN 952
            |.:.|....|.||   .....| |..|::....|........:...||             ::.:
Zfish   131 GQWMGGMRHGYGV---RQSVPY-GMATVIRSPLRTSLASLRSEQSNGS-------------VLHD 178

  Fly   953 KMFGQLSGTWDTVRIQAGELVLNRRFPKYPSSLGRQVVDHNRK--WR--SLFNNF----ESDLAN 1009
            .|....:||       .|..|||     :.|.  .:||...:|  :|  |||.:.    :|| :.
Zfish   179 HMSDSPAGT-------RGGFVLN-----FHSD--SEVVSGKKKGLFRRGSLFGSLKQLRKSD-SR 228

  Fly  1010 CTASTSSSGGNQSAGTLRKSSKPTLSTAQI---------------------------W-----NC 1042
            .:.|:..|.....|...|.||....||...                           |     |.
Zfish   229 SSISSKRSSARSDATMSRISSSDANSTISFGDGEVADEYMPAEDNVDATTTESYLGEWKNDKRNG 293

  Fly  1043 IAV------------YMSKQR-------AREGTK-PGNYFNNILLS------LPLPQ-KTSSPLA 1080
            ..|            :::.:|       ..:||| .|.|.||:|:.      :||.. ||...:.
Zfish   294 FGVSERSNGMKYEGEWINNKRHGYGCTMFPDGTKEEGKYKNNVLVRGIKKQLIPLKNTKTKQKVD 358

  Fly  1081 KA---RTTTSALSKLQTEAASALDFLGFPPRRIQSQEALNSKPGGLQRADSLISMGHNTSRDL 1140
            :|   ....||:::.:.|.|::..    ...|.:::.|..:.....|.:|    :....:|||
Zfish   359 RAVEGAIRASAIARTKVEIATSRT----AHARAKAEAADQASLSASQESD----LARAVARDL 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	ATS1	<238..>367	CDD:444065
		PH-like	616..715	CDD:473070
		COG4642	<745..890	CDD:443680	38/131 (29%)
		PLN03185	835..>962	CDD:215619	26/126 (21%)
		VPS9	1373..1479	CDD:460489
jph1b	NP_001037813.1	COG4642	<2..143	CDD:443680	40/141 (28%)
		PLN03185	38..>342	CDD:215619	76/341 (22%)