DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Als2 and morn4

DIOPT Version :9

Sequence 1:	NP_649347.1	Gene:	Als2 / 40410	FlyBaseID:	FBgn0037116	Length:	1486	Species:	Drosophila melanogaster
Sequence 2:	NP_001017559.1	Gene:	morn4 / 550131	ZFINID:	ZDB-GENE-050417-7	Length:	146	Species:	Danio rerio

Alignment Length:	156	Identity:	39/156 - (25%)
Similarity:	59/156 - (37%)	Gaps:	56/156 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   726 STGYEFSREHPKFSRVKACGTWRKGVLHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPTTGLYV 790
            |:|.|::            |.|::|..||...|::.||:.|.|..::|:..|.|.:|.|....|.
Zfish    11 SSGEEYT------------GEWKEGRRHGKGELKFADGTCYKGHFENGLFHGSGVLVFPDGSRYE 63

  Fly   791 GNFKGGRFHGHGVYEMHCKDSPESEVYEGNFCEGLFHGHGVM----------RNNRYIYVGEYQA 845
            |.|..|:|.|.|::...     :...:||.|..|...|||::          ||.
Zfish    64 GEFAQGKFQGVGIFSRF-----DGMKFEGEFKSGRVEGHGLLTFPDGSHGAPRNE---------- 113

  Fly   846 NARSGYGVIEDLVSGDKYMGMFADNK 871
                               |||.:||
Zfish   114 -------------------GMFENNK 120

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	RCC1	258..304	CDD:278826
		RCC1_2	292..321	CDD:290274
		RCC1	308..361	CDD:278826
		PH-like	616..715	CDD:302622
		VPS9	1373..1479	CDD:280383
morn4	NP_001017559.1	COG4642	6..123	CDD:226989	39/156 (25%)
		MORN	16..37	CDD:280628	7/32 (22%)
		MORN	39..61	CDD:280628	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900