Protein Alignment Als2 and rcbtb2

DIOPT Version :9

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_001004950.1
• Gene: rcbtb2 / 448359
• XenbaseID: XB-GENE-952598
• Length: 526
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 107/491 - (21%)
• Similarity: 185/491 - (37%)
• Gaps: 108/491 - (21%)

  Fly   115 DVGHPHAWQTLGFDPLELHAEGVRIRRVCCSAQG--VVFVGASGETYVMGS----CGEVFKAEQ- 172
            |||   .|......|.|   :...|::.|....|  |:::..:.|.:|||:    |.....|:.
 Frog     3 DVG---KWPIFALCPQE---DLKFIQQACVFGAGNEVLYLTKNDEVFVMGTNSSGCLGTGDAQSI 61

  Fly   173 -QPRHMRLYEEGKELLDLAAGNEHFVMLVAP----YNLADDAL-QLSVASAKEEPEDERASVKSI 231
             :||.:.:. .||.::.|:.|:...|::|..    |:...:|. ||...|..:.....:.|...|
 Frog    62 LEPRRIDML-SGKRIVSLSYGSGPHVVIVTSDGEVYSWGHNAYSQLGNGSTNQALSPCQVSTNLI 125

  Fly   232 SSGHSERSVAANTRH---LLHQGYALLHTQLFTFGASNNGLLGSGDHIRRANVMRLQK-LDSMGV 292
            :.  ...|||..:.|   |...|      :::.:|.:|:|.:|||....:....::.. |.:..|
 Frog   126 NK--KAISVACGSHHSMVLTCDG------EVYAWGYNNSGQVGSGSTANQPIPRKVTSCLQNKTV 182

  Fly   293 CSIAAGLEHTVARTLDGRLYHWGLNNHSQLGEDVS----SPMEITITENTAALPIEQNSALEATC 353
            ..||.|...::|...:|.:|.||.|.:.|||...|    :|..|...:   .:.:||     ..|
 Frog   183 IGIACGQMSSMAVVDNGEVYAWGYNGNGQLGLGSSGNQPTPCRIAALQ---GIRVEQ-----VVC 239

  Fly   354 GDYHTLLLNASGQIHSLQPAPPMRHLQQSSTYAQTLLQLQLGAAWP--------RQLRLLMCSGG 410
            |..|||.|...|.:::          ..:::|.|.....:...::|        |.:.:..|...
 Frog   240 GYAHTLALTDEGVMYA----------WGANSYGQLGTGNKSNQSYPVQVIVDKERIVEIAACHSS 294

  Fly   411 YTLQNQRQFQRQYHYYLSHLQSQLQLLLKHRQAV-------QTLEIWQRQSALEPLSALGPLLIN 468
            :|...:.|..:.|.:.....||.:...|.|....       .|..|..|..::||...|
 Frog   295 HTSAAKSQSGQVYMWGQCRGQSVITPHLTHFSCTDDVFACFSTPAIMWRLLSVEPDDHL------ 353

  Fly   469 WERILCLLVATLHSLEGFYRADFVQP--ADLLFICHYKEYIDLFDGYTKAYCDVFSVNGFGEAVV 531
                     ....||    :.:|..|  |||.|:...| ||.:.....:..|:.|
 Frog   354 ---------TVAESL----KREFDNPNTADLKFLVDEK-YIYVHKVLLQIRCEHF---------- 394

  Fly   532 AITGLSSPLAELNEESYVTRLFQQPFSIYQLFVQFM 567
                  ..|...|||. :..:.|..:.:|:.|::::
 Frog   395 ------RSLLHENEEE-IIEMNQFSYPVYRAFLEYL 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	RCC1	258..304	CDD:278826	11/46 (24%)
		RCC1_2	292..321	CDD:290274	10/28 (36%)
		RCC1	308..361	CDD:278826	18/56 (32%)
		PH-like	616..715	CDD:302622
		VPS9	1373..1479	CDD:280383
rcbtb2	NP_001004950.1	ATS1	<17..269	CDD:227511	65/278 (23%)
		RCC1	250..298	CDD:366085	7/57 (12%)
		BTB_POZ	349..465	CDD:365784	22/112 (20%)
		BACK_RCBTB2	462..526	CDD:350604

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000