DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Als2 and CG14490

DIOPT Version :9

Sequence 1:	NP_649347.1	Gene:	Als2 / 40410	FlyBaseID:	FBgn0037116	Length:	1486	Species:	Drosophila melanogaster
Sequence 2:	NP_611274.1	Gene:	CG14490 / 37041	FlyBaseID:	FBgn0034281	Length:	197	Species:	Drosophila melanogaster

Alignment Length:	176	Identity:	50/176 - (28%)
Similarity:	71/176 - (40%)	Gaps:	49/176 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   787 GLYVGNFKGGRFHGHGVYEMHCKDSPESEVYEGNFCEGLFHGHGVMRNNRY------IYVGEYQA 845
            |.|.|.:.|.:.||.||     |.:....||||::.:|..||.|.:|....      ||||:::.
  Fly    20 GQYQGKWLGQQPHGFGV-----KQTSSGLVYEGHWQKGQRHGIGSLRRKELDGRMERIYVGQWRE 79

  Fly   846 NARSGYGVIEDLVSGDKYMGMFADNKRSG-----------------------IGSCITNRGDYFE 887
            |.|||.|. :....|..|.|.:..::|||                       .|...|..|:.:.
  Fly    80 NKRSGEGK-QFYPDGSVYFGQWLADQRSGEGILWQADGGIYVGEWLRDKMHEKGLLFTATGNRYV 143

  Fly   888 GSFSGDDLTGSGVAVFENDYYYEGELTLLGPNG-RGEYYMPSGDAC 932
            |.|.|...:||||      :|:       ..|| |.::...|.|.|
  Fly   144 GQFEGGCKSGSGV------FYH-------ASNGQRIQHGFWSKDIC 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	RCC1	258..304	CDD:278826
		RCC1_2	292..321	CDD:290274
		RCC1	308..361	CDD:278826
		PH-like	616..715	CDD:302622
		VPS9	1373..1479	CDD:280383
CG14490	NP_611274.1	COG4642	35..170	CDD:226989	41/153 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900