Protein Alignment Als2 and jp

DIOPT Version :9

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_001188757.1
• Gene: jp / 34274
• FlyBaseID: FBgn0032129
• Length: 1054
• Species: Drosophila melanogaster
• Alignment Length: 887
• Identity: 171/887 - (19%)
• Similarity: 288/887 - (32%)
• Gaps: 286/887 - (32%)

  Fly   683 TPEKSFLVSTRSQEMRKVWLDQLQSSIIASLGKPLGSPVPSYRSTGYEFSREHPKFSRVKACGTW 747
            ||::      :.|:.:::...|.|.:         |..:.:|.::              :|.| .
  Fly     8 TPQQ------QQQQQQQLLQQQQQQN---------GGDLAAYAAS--------------QAAG-G 42

  Fly   748 RKGVLHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPT-TGLYVGNFKGGRFHGHGVYEMHCKDS 811
            |:|.::|..: ::.||..|||....|...|.|....|. .|.|.|.:..| |...|.|..
  Fly    43 RRGPINGGRF-DFEDGGTYCGGWDEGKAHGHGVCTGPKHQGAYAGAWNYG-FEVSGSYIW----- 100

  Fly   812 PESEVYEGNFCEGLFHGHGVMRNNRYIYVGEYQANARSG-YGVIEDLVSGDKYMGMFADNKRSGI 875
            |....|||.:..|..||.||.:..|.||.||:..:...| |||.|..||..||.|.:.:..:.|.
  Fly   101 PSGSHYEGQWQNGRRHGLGVEQIGRQIYRGEWSKDGHKGRYGVRESTVSTAKYEGTWNEGYQDGS 165

  Fly   876 GSCIT------NRGDYFEGSFSGDDLTGS---GVAVFENDYYYEGELTLL--GPNGRGEYYMPSG 929
            | |.|      .:|.:.||...|..:..|   |:|...........|:.|  |.||.....:...
  Fly   166 G-CETYADGGKYQGQWQEGKRHGYGIRTSAPFGLASHHRRKNLHASLSSLRSGENGNAAKMVEKA 229

  Fly   930 DACGGSGAMGTGEFD-------DTCELIGNKMFGQLSGTWDTVRIQAGELVLNRRFPKYPSSLGR 987
            :...| |.:.|.:.|       ...:..|.|.|                 ::|.:..|.     |
  Fly   230 EEIRG-GFVLTAKSDKLPVRRNSLTDKTGKKGF-----------------LMNLKMRKQ-----R 271

  Fly   988 QVVDHNRKWRSLFNNFESDLANCTASTSSSGGNQSAGTLRKSSKPTLSTAQIW--------NCIA 1044
            ...|..::......:..|.::  :||..|:|..||  .|...|..|.|.|...        ..:.
  Fly   272 STGDLEKRGTIASGSIRSTMS--SASWISTGSEQS--NLTTKSNHTESNASFTMEDEQLDPTVVE 332

  Fly  1045 VYMSKQRA----------------------------------REGT-KPGNYFNNILL------- 1067
            .||.:.:.                                  |:|| :.|.|.||||:
  Fly   333 TYMGEWKKDKRCGHGVAERSDGLKYEGEWYNNRKHGYGVTTFRDGTVEEGKYKNNILITSQKKKH 397

  Fly  1068 -----SLPLPQKTSSPLAKA--------RTTTSALSKLQTEAAS--------------------- 1098
                 |..|..:.::.|:.|        :.:..|:|::.|.||.
  Fly   398 LFLARSRKLRDRIAAALSSAQRALKMAMQRSDMAISRMATAAAKAQNADAAAEQARMDCENAVRM 462

  Fly  1099 ALDFL-GFPP------RRIQSQEALNSKPGGLQRADSLISMG---------------HNTSRDLD 1141
            |.:|. .|.|      .:::.:|....:||....:|:.:.||               ..||....
  Fly   463 AREFAPDFKPSVLERFEKLRFRERERFRPGPAAASDASVKMGVGLQTQQQQQQQGQFSPTSSSGS 527

  Fly  1142 NSSLASFQLDQSLMNSTVNGDESSTFNESFSKLSHNNNNSISKHMNNIDCSITSTTSTTSAVLDQ 1206
            ::.....|..|..:|.    .:........|:..|.:...:...|.:....::..|..:..|...
  Fly   528 DAYATQAQRQQQYLNM----QQQQQQQRRMSQQKHESECPVPPSMYSQQLPVSPQTDLSGMVSQA 588

  Fly  1207 VPSFGMALVLTEQDVTSIRLYLEQAFKDRHHPLYVLNERIAN-CFHYSYGYWKVKPTPILAKQAM 1270
            .||....:....|      :|.:|    :|.....||::.:| ..:.:|.:.:.:|    ..||
  Fly   589 QPSHAQVISAINQ------MYHQQ----QHQQQQQLNQQQSNPQMNPAYQFQQQQP----PGQA- 638

  Fly  1271 REWESISRRIYRFVRKMFPALPEELCQME-------------GSREVISHITLLYPLVLSEGIYS 1322
                           |:.|.|...|.|.:             |:.:|
  Fly   639 ---------------KINPNLNANLKQNQAPNQNQTQMPFGSGTNQV------------------ 670

  Fly  1323 TLFVLYANKYSRKDEMYRQNLNLAEKLKDQELVELMG---------HESFLHNVMLDPKFVESVQ 1378
            |:.........::.:..:|.|...::|:.|:.::...         |.|..||..      ..::
  Fly   671 TVSPQQQQLLQQQQQQQQQQLLQQQQLQQQQQLQQQHQGLQQQPSLHASPTHNAS------NLLR 729

  Fly  1379 TLKELQEKFSPQDMLTVIQRSTQLLTEAYEHAMAANAAQLNA 1420
            ...::|::              |:...|...|||||||.:.|
  Fly   730 RASQMQQQ--------------QIQETAAAAAMAANAAAMAA 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	RCC1	258..304	CDD:278826
		RCC1_2	292..321	CDD:290274
		RCC1	308..361	CDD:278826
		PH-like	616..715	CDD:302622	5/31 (16%)
		VPS9	1373..1479	CDD:280383	11/48 (23%)
jp	NP_001188757.1	PLN03185	46..>192	CDD:215619	49/153 (32%)
		PLN03185	333..>388	CDD:215619	8/54 (15%)
		MORN	357..379	CDD:308220	2/21 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900