Protein Alignment Als2 and LOC3290568

DIOPT Version :10

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: XP_061504334.1
• Gene: LOC3290568 / 3290568
• VectorBaseID: AGAMI1_001953
• Length: 874
• Species: Anopheles gambiae
• Alignment Length: 488
• Identity: 106/488 - (21%)
• Similarity: 167/488 - (34%)
• Gaps: 119/488 - (24%)

  Fly   752 LHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPTTGLYVGNFKGGRFHGHGVYEMHCKDSPESEV 816
            :.|..| ::.||..:||..:.....|.|....|..   .|.:.|...:|..|..::|  .|....
Mosquito    26 ISGGRY-DFEDGGTFCGGWEDNKAHGHGVCTGPKN---KGAYSGAWHYGFEVAGIYC--WPSGST 84

  Fly   817 YEGNFCEGLFHGHGVMRNNRYIYVGEYQANARSGYGVIEDLVSGDKYMGMFADNKRSGIGSCITN 881
            |||::..|..||.|:....|::|.||:....:..|||.:...|..:|.|.:|:..:.|.||....
Mosquito    85 YEGHWQNGKRHGLGLEVRGRWVYRGEWTQGFKGRYGVRQSASSTARYEGTWANGLQDGYGSETYA 149

  Fly   882 RGDYFEGSFSGDDLTGSGVAVFENDYYYEGELTLLGPNGRGEYYMPSG---------DACGGSGA 937
            .|..::|.:......|.||..             ..|.|....:.|..         .|.||:.|
Mosquito   150 DGGSYQGQWQRGMRHGYGVRT-------------SAPFGMAARFRPKSVRLSMTSLRSADGGNQA 201

  Fly   938 MGTGEFDDTCELIGNKMFGQLSGTWDTVRIQAGELVLNRRFPKYP---SSLGRQVVDHNRKWR-- 997
                ...|..|...:::        |..|   |..||..:..:.|   :||    |:..:|..
Mosquito   202 ----PTPDPGEKRNHRI--------DDAR---GGFVLKAKSDETPVRRNSL----VEKTKKGLLS 247

  Fly   998 -SLFNNFESDLANCTASTSSSG----------------------GNQSAGTLRKSSKPTLSTAQI 1039
             |:..:|:..|.|.|..|.|:.                      .::..|.........|.....
Mosquito   248 VSVLRSFDLHLLNGTMHTDSNASFIVEDEQLEASVVETYMGEWKNDKRCGYGISERSDGLKYEGE 312

  Fly  1040 WNCIAVYMSKQRA------REGTK-PGNYFNNILLSLPLPQKTSSPLAKARTTTSALSKLQTEAA 1097
            |     |.:|:..      ::||| .|.|.||:|::   .||      |........:|.:....
Mosquito   313 W-----YANKKYGYGVTTFKDGTKEEGKYKNNVLIT---SQK------KRHLFLIRSAKFRERID 363

  Fly  1098 SALDFLGFPPRRIQSQEALNSKPGGLQRADSLISMGHNTSRDLDNSSLASFQLDQSLMNS----- 1157
            :|:|            .|..|....||:||..||   .|:.....:.||....|::...|
Mosquito   364 AAVD------------SAQRSSKYALQKADIAIS---RTATARGKAELADSAADEARTESDLATR 413

  Fly  1158 ---TVNGDESSTFNESFSKLSHNNNNSISKHMN 1187
               .:..|.:.:..|.|.:|..|....:...||
Mosquito   414 LARELAPDFNPSLLERFDRLQRNRGYPLPDSMN 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	ATS1	<238..>367	CDD:444065
		PH-like	616..715	CDD:473070
		COG4642	<745..890	CDD:443680	38/137 (28%)
		PLN03185	835..>962	CDD:215619	28/135 (21%)
		VPS9	1373..1479	CDD:460489
LOC3290568	XP_061504334.1	None