DRSC/TRiP Functional Genomics Resources

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Protein Alignment Als2 and Morn1

DIOPT Version :9

Sequence 1:NP_649347.1 Gene:Als2 / 40410 FlyBaseID:FBgn0037116 Length:1486 Species:Drosophila melanogaster
Sequence 2:XP_038965637.1 Gene:Morn1 / 298676 RGDID:1359433 Length:552 Species:Rattus norvegicus


Alignment Length:457 Identity:99/457 - (21%)
Similarity:152/457 - (33%) Gaps:134/457 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   745 GTWRKGVLHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPTTGLYVGNFKGGRFHGHGVYEMHCK 809
            |.|:.|..||:..|.:.|||.|.||..:|.|.|.|                   :.|..:     
  Rat    41 GEWKGGKKHGHGKLLFKDGSYYEGEFVNGEITGEG-------------------YQHWAW----- 81

  Fly   810 DSPESEVYEGNFCEGLFHGHGVMRNNRY----IYVGEYQANARSGYGVIEDLVSGDKYMGMFADN 870
               ....|.|.|..|...|||:|   :|    .|.||.....|.|.|.:|| ..|..|.|.|.||
  Rat    82 ---SGNTYSGQFVLGEPQGHGIM---KYKAGGHYEGELSQGLREGQGFLED-QDGQVYQGSFHDN 139

  Fly   871 KRSGIGSCITNRGDYFEGSFSGDDLTGSGVAVFENDYYYEGELTLLGPNGRGEYYMPSGDACGGS 935
            ||.|.|..:...||.:||.:..|...|.||....:...|:|:       ...:.:...|.....|
  Rat   140 KRHGRGQMVFKNGDKYEGDWVRDQRQGHGVLFCADGSTYKGQ-------WHNDVFSGLGSLVHCS 197

  Fly   936 GAMGTGEFDD--------TCELIGNKMFGQLSGTWDTVRIQA----GELVLNR------------ 976
            |....|.|.:        ...::|.::...:.|:..|:.:|.    ||:..:.            
  Rat   198 GVTYCGMFINGHPAAQAKKIVVLGPELLEVVQGSPFTLSVQLQQDDGEVAKSESGRVLKISAGVR 262

  Fly   977 --RFPKYPSSLGRQVVDHNRKWRSLFNNFESDLANCTASTSSSGGNQSAGTLRKSSKP-TLSTAQ 1038
              :.|:|                |..:.|:.|.|:......:..|.|..        | .||.:.
  Rat   263 YVQLPEY----------------SEVSFFKMDDAHMETPIQTPFGFQCI--------PYPLSVST 303

  Fly  1039 IWNCIAVYMSKQRAREGTKPGNYFNNILLSLPLPQKTSSPLAKART------------------- 1084
            .|              |.:||:...:....|.|.:|.|.|:..:..                   
  Rat   304 SW--------------GLEPGSTVESARADLLLSKKDSEPVLDSEAFHGKGDTLSILPARRHEPC 354

  Fly  1085 TTSALSKLQTEAASALDF-LGFPPRRIQSQ-------EALNSKPGGLQRADSLISMGHNTSRDLD 1141
            .::|..::....|..:|. ||.||..:|..       |...::|.|.:....::|......|..:
  Rat   355 CSAAYQRVDQGCAEFVDIHLGAPPPGMQPYLFLPSMLEKAGNRPKGDRSPPEVLSTAQEPLRGTN 419

  Fly  1142 NS 1143
            .|
  Rat   420 RS 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Als2NP_649347.1 RCC1 258..304 CDD:278826
RCC1_2 292..321 CDD:290274
RCC1 308..361 CDD:278826
PH-like 616..715 CDD:302622
VPS9 1373..1479 CDD:280383
Morn1XP_038965637.1 PLN03185 58..>208 CDD:215619 53/187 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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