DRSC/TRiP Functional Genomics Resources

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Protein Alignment Als2 and Rsph1

DIOPT Version :9

Sequence 1:NP_649347.1 Gene:Als2 / 40410 FlyBaseID:FBgn0037116 Length:1486 Species:Drosophila melanogaster
Sequence 2:NP_079566.1 Gene:Rsph1 / 22092 MGIID:1194909 Length:301 Species:Mus musculus


Alignment Length:293 Identity:66/293 - (22%)
Similarity:107/293 - (36%) Gaps:52/293 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   750 GVLHGNCYLEYPDGSVYCGELQHGIIEGFGKMVIPTTGLYVGNFKGGRFHGHGVYEMHCKDSPES 814
            |..||:.....|:|..|.|..:.|...|.|.........|.|::...:.||.|.:..     |:.
Mouse    28 GERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNKKHGQGTFIY-----PDG 87

  Fly   815 EVYEGNFCEGLFHGHGVMRN-NRYIYVGEYQANARSGYGVIEDLVSGDKYMGMFADNKRSGIGSC 878
            ..|||.:.:...||.||... |...|.||:..:.|.|.|......:|.||:|.:...::.|....
Mouse    88 SRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETGSKYVGTWVHGQQEGAAEL 152

  Fly   879 ITNRGDYFEGSFSGDDLTGSGVAVFENDYYYEGELTLLGPNGRGEYYMPSGDACGGSGAMGTGEF 943
            | :....::|.|...:..|.|..||:           :|....|||.:...:         .||.
Mouse   153 I-HLNHRYQGKFMNKNPVGPGKYVFD-----------IGCEQHGEYRLTDTE---------RGEE 196

  Fly   944 DDTCELIGNKMFGQLSGTWDTVRIQAGEL---VLNRRFPKYPSSLGRQ-------VVDHNRKWRS 998
            ::..|.:.|     :...|..:.|....|   .|:...|. |...|::       |.|.:...::
Mouse   197 EEEEETLVN-----IVPKWKALNITELALWTPTLSEEQPP-PEGQGQEEPQGLTGVGDPSEDIQA 255

  Fly   999 LFNNFESDLANCTASTSSSGGNQSAGTLRKSSK 1031
              ..||.:|       ...|.::...|.|:.|:
Mouse   256 --EGFEGEL-------EPRGADEDVDTFRQESQ 279

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Als2NP_649347.1 RCC1 258..304 CDD:278826
RCC1_2 292..321 CDD:290274
RCC1 308..361 CDD:278826
PH-like 616..715 CDD:302622
VPS9 1373..1479 CDD:280383
Rsph1NP_079566.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..41 4/12 (33%)
MORN 1 20..43 5/14 (36%)
COG4642 37..172 CDD:226989 36/140 (26%)
MORN 42..63 CDD:197832 5/20 (25%)
MORN 2 44..66 5/21 (24%)
MORN 67..89 CDD:280628 6/26 (23%)
MORN 3 67..89 6/26 (23%)
MORN 88..109 CDD:197832 7/20 (35%)
MORN 4 90..112 8/21 (38%)
MORN 111..131 CDD:197832 6/19 (32%)
MORN 5 113..135 6/21 (29%)
MORN 6 159..181 7/32 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 225..301 13/65 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4642
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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