Protein Alignment Als2 and K11D2.1

DIOPT Version :10

• Sequence 1: NP_649347.1
• Gene: Als2 / 40410
• FlyBaseID: FBgn0037116
• Length: 1486
• Species: Drosophila melanogaster
• Sequence 2: NP_001368497.1
• Gene: K11D2.1 / 187290
• WormBaseID: WBGene00010768
• Length: 278
• Species: Caenorhabditis elegans
• Alignment Length: 248
• Identity: 64/248 - (25%)
• Similarity: 99/248 - (39%)
• Gaps: 64/248 - (25%)

  Fly   176 HMRLYEEGKEL----LDLAAGNEHFVMLVAPYNLADDALQLSVASAKEEPEDERASVKS------ 230
            ||.:..:.::|    ||...||..|:      :|..|...|.||:::|....||:...|
 Worm    50 HMAILMKHEKLAVRRLDDFEGNLTFL------DLHTDLDVLLVATSREIYAVERSGTSSEIVKIL 108

  Fly   231 -ISSGHSER-----------------SVAANTRHLLHQGYALLHTQLFTFGASNNGLLGSGDHIR 277
             .|.|.|.:                 ..||....|:.:...   ..||:.|....|.||.| .||
 Worm   109 VDSVGISPKKNNLANKIQFPWPVRIVEAAAGHDFLIFRDTT---GNLFSMGTGTRGELGVG-LIR 169

  Fly   278 RAN-VMRLQKLDSMGVCSIAAGLEHTVARTLDGRLYHWGLNNHSQLGEDVSSPMEITITENTAAL 341
            |.: .:.:::|..:.:..:|.|..||||.|..|..|.||.|.:.|||:|..|         |...
 Worm   170 RVDEPVHIEQLVGIRIKKVACGGWHTVALTEGGDAYTWGWNRYGQLGKDKGS---------TEVY 225

  Fly   342 PI----------EQNSALEATCGDYHTLLLNASGQ---IHSLQPAPPMR--HL 379
            |:          |:| .|:..|.:::|.::..:|.   :....|.||:.  ||
 Worm   226 PVLIDPEEEKFGEEN-ILDVACTEHNTQIVIKTGHAPFVLGTNPTPPINEFHL 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Als2	NP_649347.1	ATS1	<238..>367	CDD:444065	39/159 (25%)
		PH-like	616..715	CDD:473070
		COG4642	<745..890	CDD:443680
		PLN03185	835..>962	CDD:215619
		VPS9	1373..1479	CDD:460489
K11D2.1	NP_001368497.1	ATS1	<128..>251	CDD:444065	37/136 (27%)