back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Als2 and Rcc2

DIOPT Version :10

Sequence 1:	NP_649347.1	Gene:	Als2 / 40410	FlyBaseID:	FBgn0037116	Length:	1486	Species:	Drosophila melanogaster
Sequence 2:	NP_776292.1	Gene:	Rcc2 / 108911	MGIID:	1919784	Length:	520	Species:	Mus musculus

Alignment Length:	362	Identity:	76/362 - (20%)
Similarity:	120/362 - (33%)	Gaps:	129/362 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AGGELLLLTTDHALYSAKLQANREHMDLQLLRTDVVDMDFCSGSQELFVVLTNGSV-------QR 107
            ||...::...:|.....||:.::                 |.| |.|....||..:       ::
Mouse    77 AGAAAIITEPEHTKERVKLEGSK-----------------CKG-QLLIFGATNWDLIGRKEVPKQ 123

  Fly   108 QAT--GSGRDVGHPHAWQTLGFDPLELHAEGVRIRRVCCSAQGVVFVGASGETYVMGSCGEVFKA 170
            ||.  ..|:::..||.:..|         .|||:|                 |.|.|||.
Mouse   124 QAAYRNLGQNLWGPHRYGCL---------SGVRVR-----------------TVVSGSCA----- 157

  Fly   171 EQQPRHMRLYEEGK-------ELLDLAAGNEHFVMLVAPYNLADDALQLSVASAKEEPEDERASV 228
               ...:.:..|||       |...|..|:...|                     |.|.    .:
Mouse   158 ---AHSLLITTEGKLWSWGRNEKGQLGHGDTKRV---------------------EAPR----LI 194

  Fly   229 KSISSGHSERSVAANTR-HLLHQGYALLHT-QLFTFGASNNGLLGSGDHI----RRANVMRLQKL 287
            :::|  |....:||..| |.|    ||..| .:|.||.:..|.||.|:..    ..|.:|    .
Mouse   195 EALS--HEAIVLAACGRNHTL----ALTDTGSVFAFGENKMGQLGLGNQTDAVPSPAQIM----Y 249

  Fly   288 DSMGVCSIAAGLEHTVARTLDGRLYHWGLNNHSQLGEDVSS----------------PMEITI-- 334
            :...:..:|.|.|.::.....|.||.:|...:.|||.:...                |..:.|
Mouse   250 NGQPITKMACGAEFSMLMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFI 314

  Fly   335 --TENTAALPIEQNSALEATCGDYHTLLLNASGQIHS 369
              |::...||:......:..||..|||:|::..::.|
Mouse   315 EKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFS 351

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.