Sequence 1: | NP_649346.1 | Gene: | CG11249 / 40409 | FlyBaseID: | FBgn0037115 | Length: | 642 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_000289.1 | Gene: | PKLR / 5313 | HGNCID: | 9020 | Length: | 574 | Species: | Homo sapiens |
Alignment Length: | 493 | Identity: | 109/493 - (22%) |
---|---|---|---|
Similarity: | 204/493 - (41%) | Gaps: | 72/493 - (14%) |
- Green bases have known domain annotations that are detailed below.
Fly 151 IKHHLLGGVRCFMVNLFEGTQHDNQSLIVKLREA-EISVSKELGF-PVTSSVMVKISPRHQFTGG 213
Fly 214 FSTQFRQEGKKC-VELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED--IQ 275
Fly 276 LMVRSIHADHLKGCVARGGMLYAHMPVLFP-ARCRRFRISYEELEDLTFAREVGLNVVVSHIVGT 339
Fly 340 PKYVDNLEHAMSAMHCDGMRLYARVVLNEVQGCKGELNWAIKRYDGFLVELAEPATVP--DIMHL 402
Fly 403 CPDAECFMQLTY------AAKKPIIFDPRLLDEQKLRVDPAHYYYTFY----------------- 444
Fly 445 ----YPDKYV----TTCPQPKGTIYFRLLQSAIFEQISPTA-LANTPYCDRSHTGADSLARSVVT 500
Fly 501 ASIEVHAVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTKCIIAHR 565
Fly 566 RNVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGTKF 603 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG11249 | NP_649346.1 | Pyruvate_Kinase | 158..>332 | CDD:304951 | 52/179 (29%) |
PK_C | 492..594 | CDD:280960 | 25/101 (25%) | ||
PKLR | NP_000289.1 | Pyruvate_Kinase | 85..573 | CDD:238178 | 109/493 (22%) |
Fructose-1,6-bisphosphate binding, allosteric activator. /evidence=ECO:0000269|PubMed:11960989, ECO:0007744|PDB:2VGF | 475..480 | 1/4 (25%) | |||
Fructose-1,6-bisphosphate binding, allosteric activator. /evidence=ECO:0000269|PubMed:11960989, ECO:0007744|PDB:2VGF | 559..564 | 1/4 (25%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0469 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.770 |