Protein Alignment CG11249 and CG2964

DIOPT Version :9

• Sequence 1: NP_649346.1
• Gene: CG11249 / 40409
• FlyBaseID: FBgn0037115
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 109/557 - (19%)
• Similarity: 205/557 - (36%)
• Gaps: 98/557 - (17%)

  Fly   105 CNISFEEDRWHGFFKDFQILTTPVGTDPNENRKCVELTSMTNCDLEIKHHLLGGVRCFMVNLFEG 169
            |.:...:...|      |.|.:.:.|....:|....:.:|          ::.||..|.:| |..
  Fly    20 CELDLAQQASH------QRLVSLIATISVSSRNADTIYTM----------IMRGVNIFRLN-FSH 67

  Fly   170 TQHDNQSLIVKL-REAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQFRQEGKKCVELVQGQK 233
            ..|:..|..::| .||...:.||.|...|.::..........||.....        |.|..|..
  Fly    68 ESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDGD--------VFLRSGDN 124

  Fly   234 VILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQLMVRSIHADHLKGCVARGGMLY 297
            :.|:::|...|:.|.:.:||:...:|......|.:.|.:. :.|.:..:..|.|...|..||.|.
  Fly   125 LRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLN 189

  Fly   298 AHMPVLFP-ARCRRFRISYEELEDLTFAREVGLNVVVSHIVGTPKYVDNLEHAMSAMHCDGMRLY 361
            .:..|:.| .......:|.:::.|:.|:.:..::.:.:..|.:.|.|..|
  Fly   190 NNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKEL--------------- 239

  Fly   362 ARVVLNEVQG------CKGELNWAIKRY-------DGFLVELAEPATVPDIMHLCPDAECFMQLT 413
             |.||.| :|      .|.:...|:.|:       ||.|:..|:..|...|..|....:..:...
  Fly   240 -RTVLGE-KGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQC 302

  Fly   414 YAAKKPIIFDPRLLDEQKLRVDP---------------------AHYYYTFYYPDKYVTTCP--- 454
            ....||:|....:|:..:....|                     :.......:|.:.|.||.
  Fly   303 NKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLC 367

  Fly   455 -QPKGTIYFRLLQSAIFEQISPTALANTPYCDRSHTGADSLARSVVTASIEVHAVAIVVIGVTTR 518
             :.:..::||.|.|.:..::...       .|.:|    |||.:.|..:...:|..|:|:..:.|
  Fly   368 REAEKVLWFRDLFSDLVSEVRGE-------LDAAH----SLAIAAVETAKRTNATLIIVLTTSGR 421

  Fly   519 MVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTKCIIAHRRNVFLKAIYALAYLVKRK 583
            ....:|.|||..||:.::.......:|.::..|..:.:..:....:..:|..:..:|:....|..
  Fly   422 SATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDVDARVQFAMTSAKKWG 486

  Fly   584 IAKQNDQVILVYNYEDGTKFPEK----YIVYKLDRTN 616
            |....|.:::|..::||..|...    |..::.||.:
  Fly   487 IIDDGDPIVIVSAWKDGGGFTNNVRVVYAFFEADRVD 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11249	NP_649346.1	Pyruvate_Kinase	158..>332	CDD:304951	40/176 (23%)
		PK_C	492..594	CDD:280960	21/101 (21%)
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	103/529 (19%)
		pyruv_kin	32..512	CDD:273424	103/526 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810