Protein Alignment CG11249 and Pklr

DIOPT Version :9

• Sequence 1: NP_649346.1
• Gene: CG11249 / 40409
• FlyBaseID: FBgn0037115
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_006232655.1
• Gene: Pklr / 24651
• RGDID: 3336
• Length: 574
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 103/499 - (20%)
• Similarity: 200/499 - (40%)
• Gaps: 84/499 - (16%)

  Fly   151 IKHHLLGGVRCFMVNLFEGTQHDNQSLIVKLREA-EISVSKELGF-PVTSSVMVKISPRHQFTGG 213
            :|..:..|:....:|...|:...:...|..:||| |...:..|.: ||..::..| .|.
  Rat   104 LKEMIKAGMNIARLNFSHGSHEYHAESIANIREATESFATSPLSYRPVAIALDTK-GPE------ 161

  Fly   214 FSTQFRQEGKKC-VELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLD-FILIG----- 271
            ..|...|.|.:. ||:|:|.:|::|||.::..|.:|..::       ||.|.:. .:.:|
  Rat   162 IRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDAKTVW-------VDYHNITRVVAVGGRIYI 219

  Fly   272 ED--IQLMVRSIHADHLKGCVARGGMLYAHMPVLFP-ARCRRFRISYEELEDLTFAREVGLNVVV 333
            :|  |.|:|:.|..:.|...|..||:|.:...|..| .......:|.::|.||.|..:..::::.
  Rat   220 DDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLPGLSEQDLLDLRFGVQHNVDIIF 284

  Fly   334 SHIVGTPKYVDNLEHAMSAMHCDGMRLYARVVLNEVQGCKGELNWAIKRYDGFLVELAEPATVP- 397
            :..|   :...::.....|:..:|..:   .::::::..:|     :|::|..| |:::...|.
  Rat   285 ASFV---RKASDVLAVRDALGPEGQNI---KIISKIENHEG-----VKKFDEIL-EVSDGIMVAR 337

  Fly   398 -DIMHLCPDAECFMQLTY------AAKKPIIFDPRLLDEQKLRVDPAHYYYTFY----------- 444
             |:....|..:.|:....      .|.||::...::|:....:..|.....:..
  Rat   338 GDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVANAVLDGADCI 402

  Fly   445 ----------YPDKYV----TTCPQPKGTIYFRLLQSAIFEQISPTA-LANTPYCDRSHTGADSL 494
                      :|.:.|    ....:.:..:|.|.|    ||::...| |:..|        .:..
  Rat   403 MLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQL----FEELRRAAPLSRDP--------TEVT 455

  Fly   495 ARSVVTASIEVHAVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTK 559
            |...|.||.:..|.||:|:..|.|..|.:|.:||.|.::.|:....|...|.:...|..|.:|..
  Rat   456 AIGAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREP 520

  Fly   560 CIIAHRRNVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGTKF 603
            .......:|..:..:.:.....|...:..|.||:|..:..|:.:
  Rat   521 PEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGY 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11249	NP_649346.1	Pyruvate_Kinase	158..>332	CDD:304951	47/185 (25%)
		PK_C	492..594	CDD:280960	26/101 (26%)
Pklr	XP_006232655.1	Pyruvate_Kinase	85..573	CDD:238178	103/499 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770