Protein Alignment CG11249 and Pkm

DIOPT Version :9

• Sequence 1: NP_649346.1
• Gene: CG11249 / 40409
• FlyBaseID: FBgn0037115
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_011240976.2
• Gene: Pkm / 18746
• MGIID: 97591
• Length: 604
• Species: Mus musculus
• Alignment Length: 493
• Identity: 101/493 - (20%)
• Similarity: 202/493 - (40%)
• Gaps: 72/493 - (14%)

  Fly   151 IKHHLLGGVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKE--LGFPVTSSVMVKISPRHQFTGG 213
            :|..:..|:....:|...||...:...|..:|||..|.:.:  |..||..::..| .|..: ||
Mouse   134 LKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTK-GPEIR-TG- 195

  Fly   214 FSTQFRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFL--IVDVHPLDFILIGED--I 274
               ..:..|...|||.:|..:.:|:|..|.::.:.::::::.:.:  :|:|....::   :|  |
Mouse   196 ---LIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYV---DDGLI 254

  Fly   275 QLMVRSIHADHLKGCVARGGMLYAHMPVLFP-ARCRRFRISYEELEDLTFAREVGLNVVVSHIVG 338
            .|.|:...||.|...|..||.|.:...|..| |......:|.::::||.|..|..:::|.:..:.
Mouse   255 SLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIR 319

  Fly   339 TPKYVDNLEHAMSAMHCDGMRLYARVVLNEVQGCKGELNWAIKRYDGFLVELAEPATVP--DIMH 401
            ....|..:...:..   .|..:   .::::::..:|     ::|:|..| |.::...|.  |:..
Mouse   320 KAADVHEVRKVLGE---KGKNI---KIISKIENHEG-----VRRFDEIL-EASDGIMVARGDLGI 372

  Fly   402 LCPDAECFMQLTY------AAKKPIIFDPRLLDEQKLRVDPAHYYYTFY---------------- 444
            ..|..:.|:....      .|.||:|...::|:....:..|.....:..
Mouse   373 EIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGE 437

  Fly   445 -----YPDKYV----TTCPQPKGTIYFRLLQSAIFEQISPTALANTPYCDRSHTGADSLARSVVT 500
                 ||.:.|    ....:.:..||.  ||  :||::...|...:...:.:..||       |.
Mouse   438 TAKGDYPLEAVRMQHLIAREAEAAIYH--LQ--LFEELRRLAPITSDPTEAAAVGA-------VE 491

  Fly   501 ASIEVHAVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTKCIIAHR 565
            ||.:..:.||:|:..:.|...:::.:||.|||:.|:..........:|..:..:..:...:.|..
Mouse   492 ASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLNAWA 556

  Fly   566 RNVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGTKF 603
            .:|.|:...|:.....|...|:.|.||::..:..|:.|
Mouse   557 EDVDLRVNLAMDVGKARGFFKKGDVVIVLTGWRPGSGF 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11249	NP_649346.1	Pyruvate_Kinase	158..>332	CDD:304951	45/180 (25%)
		PK_C	492..594	CDD:280960	23/101 (23%)
Pkm	XP_011240976.2	Pyruvate_Kinase	115..603	CDD:238178	101/493 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770