Protein Alignment CG11249 and pklr

DIOPT Version :9

• Sequence 1: NP_649346.1
• Gene: CG11249 / 40409
• FlyBaseID: FBgn0037115
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_958446.1
• Gene: pklr / 114551
• ZFINID: ZDB-GENE-010907-1
• Length: 538
• Species: Danio rerio
• Alignment Length: 580
• Identity: 111/580 - (19%)
• Similarity: 212/580 - (36%)
• Gaps: 100/580 - (17%)

  Fly    64 MNRGSEMAILRSKYSLHSGFNQNCSSASEEELDFEELSEDPCNISFEEDRWHGFFKDFQILTTPV 128
            :.|.||:..|...:......:.:.:....|.|...::.::|...           ::..|:.| :
Zfish     5 IRRYSEVMALPDSFIQKQQLDASMADTFLEHLCLLDIDQEPITA-----------RNTSIICT-I 57

  Fly   129 GTDPNENRKCVELTSMTNCDLEIKHHLLGGVRCFMVNLFEGTQHDNQSLIVKLREA-EISVSKEL 192
            |.   .:|...:|..|....:.|..          :|...||...:...|..:||| |...|..|
Zfish    58 GP---ASRSITKLQEMVKAGMNIAR----------LNFSHGTHQYHAETIRNVREAVETLTSDPL 109

  Fly   193 GF-PVTSSVMVKISPRHQFTGGFSTQFRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVN-- 254
            .: ||..::..| .|..: ||....:...|    |.|.:|..|.:.......::::..||:::
Zfish   110 YYRPVAIALDTK-GPEIR-TGLVKGRADAE----VTLERGALVRVVTAECEREQTDGSVIWMDYP 168

  Fly   255 --ARFLIVDVHPLDFILIGED-IQLMVRSIHADHLKGCVARGGMLYAHMPVLFPAR--CRRFRIS 314
              .|.|..|..    |.|.:. :.|.|..|....|:..|..||:|.:...|..|..  .....:|
Zfish   169 SLTRVLKKDSR----IYIDDGLLALRVLEIGDSWLQARVENGGVLGSSKGVNLPGAELLDLPAVS 229

  Fly   315 YEELEDLTFAREVGLNVVVSHIVGTPKYVDNLEHAMSAMHCDGMRLYARVVLNEVQGCKGELNW- 378
            ..:..||.|..|..::::.:..:...:.|..:..|:      |.:.:...::::|:..:|..|:
Zfish   230 ERDRSDLQFGVEQQVDMIFASFIRCAEDVRAVRDAL------GPQGHDIKIISKVESRQGVRNFE 288

  Fly   379 -AIKRYDGFLVELAE-----PATVPDIMHLCPDAECFMQLTYAAKKPIIFDPRLLDEQKLRVDPA 437
             .::..||.:|...:     ||....|........|     .:|.||:|...::|:.......|.
Zfish   289 QVLQESDGVMVARGDLGIEIPAEKVFIAQKMMIGRC-----NSAGKPVICATQMLESMVHHARPT 348

  Fly   438 HYYYT---------------------FYYPDKYV----TTCPQPKGTIYFRLLQSAIFEQISP-T 476
            ....:                     .::|.:.|    :.|.:.:..|:.:.|    ||::.. |
Zfish   349 RAESSDVANAVLDGADCVMLSGETAKGHFPVEAVAMMHSICREAEAAIFHQQL----FEELRRLT 409

  Fly   477 ALANTPYCDRSHTGADSLARSVVTASIEVHAVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSA 541
            .|::.|        .:..|...|.:|.:..|.||:::..:.|..|.:|.:||..||:.|:.....
Zfish   410 PLSSDP--------TEVTAIGAVESSYKCCAGAIIILTTSGRSAQLLSRYRPRCPIIAVTRNAQV 466

  Fly   542 EDYVSIYHNVTMLPFRTKCIIAHRRNVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGT 601
            .....:...|....||.........:|..:..:|:.....|...:..|.||:|..:..|:
Zfish   467 ARQSQLLRGVFPALFRAPPAEVWADDVDNRVTFAMDIGKARGFFRSGDMVIVVTGWSPGS 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11249	NP_649346.1	Pyruvate_Kinase	158..>332	CDD:304951	43/182 (24%)
		PK_C	492..594	CDD:280960	23/101 (23%)
pklr	NP_958446.1	Pyruvate_Kinase	48..537	CDD:238178	104/537 (19%)
		pyruv_kin	49..533	CDD:273424	104/525 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.770