Protein Alignment CG11249 and pklr

DIOPT Version :10

• Sequence 1: NP_649346.1
• Gene: CG11249 / 40409
• FlyBaseID: FBgn0037115
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_031747000.1
• Gene: pklr / 100380137
• XenbaseID: XB-GENE-5918041
• Length: 549
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 111/499 - (22%)
• Similarity: 192/499 - (38%)
• Gaps: 84/499 - (16%)

  Fly   151 IKHHLLGGVRCFMVNLFEGTQHDNQSLIVKLREA-EISVSKELGF-PVTSSVMVKISPRHQFTGG 213
            :|..:..|:....:|...|:...:...|..:|:| |...|....: ||..::..| .|..: ||.
 Frog    79 LKEMIKAGMNIARLNFSHGSHEYHAGSIQNIRDATESFASNPTHYRPVAIALDTK-GPEIR-TGV 141

  Fly   214 FSTQFRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFL--IVDVHPLDFILIGED--I 274
            ..|....|    |||.:|..|.:|.|..:.|:.:...::|:.:.:  :|.|....|:   :|  |
 Frog   142 IKTGENAE----VELAKGSVVKVTTDESFKDKCDEQTLWVDYKNISKVVKVGGRIFV---DDGLI 199

  Fly   275 QLMVRSIHADHLKGCVARGGMLYAHMPVLFP-ARCRRFRISYEELEDLTFAREVGLNVVVSHIVG 338
            .|:|:.|..|:....|..||.|.:...|..| |:.....:|..:..||.|..|.|:::|.:..:.
 Frog   200 SLLVKEIGPDYCMTEVENGGNLCSKKGVNLPGAQVDLPALSERDCLDLQFGIEQGVDMVFASFIR 264

  Fly   339 TPKYVDNLEHAMSAMHCDGMRLYARVVLNEVQG-----CKGELNWAIKRYDGFLVELAEPATVP- 397
            ..:.|    ||:            |..|.|..|     .|.|.:..:||:|..| |.::...|.
 Frog   265 KAQDV----HAI------------RQKLGEKGGNIRIISKIENHEGVKRFDEIL-EASDGIMVAR 312

  Fly   398 -DIMHLCPDAECFMQLTY------AAKKPIIFDPRLLDEQKLRVDPAHYYYT------------- 442
             |:....|..:.|:....      .|.||:|...::|:....:..|.....:
 Frog   313 GDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAESSDVANAVLDGADCI 377

  Fly   443 --------FYYPDKYV----TTCPQPKGTIYFRLLQSAIFEQI-SPTALANTPYCDRSHTGADSL 494
                    ..||.:.|    ....:.:..||    ...:||:: ..|.|...|        .:..
 Frog   378 MLSGETAKGLYPLESVHMQHAIAREAEAAIY----NQQLFEELRRVTPLTQDP--------TEVT 430

  Fly   495 ARSVVTASIEVHAVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTK 559
            |...|.||.:..|.||:|:..:.|..|.:|.:||.|||:.|:..........:...|..:.:|..
 Frog   431 AIGAVEASFKCCAGAIIVLTTSGRSAQHLSRYRPRAPIIAVTRNAQVARQAHLNRGVFPVLYREA 495

  Fly   560 CIIAHRRNVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGTKF 603
            ...|...:|..:..:.::....|....::|.||:|..:..|:.|
 Frog   496 QQEAWADDVDRRVQFGISIGKVRGFLSKDDIVIIVTGWRPGSGF 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11249	NP_649346.1	Pyruvate_Kinase	158..>332	CDD:453956	47/180 (26%)
		PK_C	492..594	CDD:460738	25/101 (25%)
pklr	XP_031747000.1	Pyruvate_Kinase	60..548	CDD:238178	111/499 (22%)