Protein Alignment ORMDL and Ormdl3

DIOPT Version :10

• Sequence 1: NP_730669.1
• Gene: ORMDL / 40404
• FlyBaseID: FBgn0037110
• Length: 154
• Species: Drosophila melanogaster
• Sequence 2: NP_001400222.1
• Gene: Ormdl3 / 360618
• RGDID: 1560577
• Length: 153
• Species: Rattus norvegicus
• Alignment Length: 152
• Identity: 77/152 - (50%)
• Similarity: 106/152 - (69%)
• Gaps: 0/152 - (0%)

  Fly     3 SIAGGHGEANPNSSWLSARGFWLAYLLGLLSVHLLFLSVPFVSIPWAWTATNLLHNAAHLYFLHV 67
            ::...|.|.|||:..:::||.||:|:|.:..:|::.||:||||:|..||.|||:||.....|||.
  Rat     2 NVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHT 66

  Fly    68 IKGAPWLSTENDPSRRWTHWEQIDDGVQMTTTRKFLTAVPIVLFLLTCLYTRNNTEHFIPNFISL 132
            :||.|:.:.:...:|..|||||:|.|||.|.:|||||..||||:.||..||:.:..|||.|.:||
  Rat    67 VKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSL 131

  Fly   133 VVVTLPKLPQFHGVRLFNINKY 154
            :.|.:|||||.||||:|.||||
  Rat   132 MSVLIPKLPQLHGVRIFGINKY 153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORMDL	NP_730669.1	ORMDL	12..147	CDD:461151	68/134 (51%)
Ormdl3	NP_001400222.1	Important for ceramide level-sensing. /evidence=ECO:0000250|UniProtKB:Q8N138	1..17		5/14 (36%)
		ORMDL	11..146	CDD:461151	68/134 (51%)