Protein Alignment ORMDL and ORMDL2

DIOPT Version :9

• Sequence 1: NP_730669.1
• Gene: ORMDL / 40404
• FlyBaseID: FBgn0037110
• Length: 154
• Species: Drosophila melanogaster
• Sequence 2: NP_054901.1
• Gene: ORMDL2 / 29095
• HGNCID: 16037
• Length: 153
• Species: Homo sapiens
• Alignment Length: 154
• Identity: 80/154 - (51%)
• Similarity: 108/154 - (70%)
• Gaps: 4/154 - (2%)

  Fly     3 SIAGGHGEANPNSSWLSARGFWLAY--LLGLLSVHLLFLSVPFVSIPWAWTATNLLHNAAHLYFL 65
            ::...|.|.|||:..:::||.||||  |:|||  |::.||:||.|||..||.||::||.|...||
Human     2 NVGVAHSEVNPNTRVMNSRGIWLAYIILVGLL--HMVLLSIPFFSIPVVWTLTNVIHNLATYVFL 64

  Fly    66 HVIKGAPWLSTENDPSRRWTHWEQIDDGVQMTTTRKFLTAVPIVLFLLTCLYTRNNTEHFIPNFI 130
            |.:||.|:.:.:...:|..|||||:|.|:|.|::||||:..||||:||...||:.:..||:.|..
Human    65 HTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTA 129

  Fly   131 SLVVVTLPKLPQFHGVRLFNINKY 154
            ||:.|.|||||||||||:|.||||
Human   130 SLLSVLLPKLPQFHGVRVFGINKY 153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORMDL	NP_730669.1	ORMDL	12..147	CDD:281982	71/136 (52%)
ORMDL2	NP_054901.1	ORMDL	11..146	CDD:281982	71/136 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4179
eggNOG	1	0.900	-	-		E1_COG5081
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4080
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54404
OrthoDB	1	1.010	-	-		D1405600at2759
OrthoFinder	1	1.000	-	-		FOG0001304
OrthoInspector	1	1.000	-	-		otm41169
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12665
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1721
SonicParanoid	1	1.000	-	-		X1334
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.970