DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg11 and ALG1L2

DIOPT Version :9

Sequence 1:	NP_001262182.1	Gene:	Alg11 / 40402	FlyBaseID:	FBgn0037108	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001129624.1	Gene:	ALG1L2 / 644974	HGNCID:	37258	Length:	215	Species:	Homo sapiens

Alignment Length:	107	Identity:	21/107 - (19%)
Similarity:	42/107 - (39%)	Gaps:	34/107 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 LKQRH---------WIEAKNYPHFTLLGQSIGSMVVGLEALCRFPPDIYIDTMGYAFTYP----- 165
            :.|:|         |:|.:..|  .|||.      |.|        |:.:||.......|
Human   117 IHQKHFQHIQVCIPWLEGRGLP--PLLGS------VDL--------DVCLDTSSSGLDLPMKVVD 165

  Fly   166 LFRYLAQSKVGCYVHYPVISTDMLKRVQQRQMSHNNKKYVAR 207
            :||....:   |.|::..:. :::|..:.|.:..::::..|:
Human   166 MFRCCLPA---CAVNFKCLH-ELVKHEENRLVFEDSEELAAQ 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg11	NP_001262182.1	PLN02949	24..473	CDD:215511	21/107 (20%)
Alg11	NP_001262182.1	GT1_ALG11_like	44..463	CDD:99978	21/107 (20%)
ALG1L2	NP_001129624.1	Glycosyltransferase_GTB_type	<8..206	CDD:299143	21/107 (20%)
ALG1L2	NP_001129624.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	40..66
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900